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. Author manuscript; available in PMC: 2016 Sep 14.
Published in final edited form as: Biomacromolecules. 2015 Aug 17;16(9):2684–2692. doi: 10.1021/acs.biomac.5b00557

Figure 1.

Figure 1

Screening studies for a heparin-mimicking polymer. Proliferation studies of BaF3-FR1C cells in the presence of 1 ng/mL bFGF and various concentrations of pSS (a), pSPM or pAMPS (b), pVS or pAHPS polymers (c). Incubation of 20,000 cells/well in 96-well plate with each of the samples was carried out for 48 hours. CellTiter®-Blue assay was performed to quantify the extent of cell growth. Samples with heparin were used as positive control groups. Data was normalized to the blank medium group, which was set at 100%. Each sample had four replicates. Error bars represent STDEV. Statistical analysis was performed using Student’s t-test; p < 0.05 was consider significant. The percent cell growth from each polymer was compared to the control group, which had heparin at the same concentration. All polymers were significantly different than heparin except for pVS at 200 µg/mL, 0.5 µg/mL, and 0.02 µg/mL.