Retraction of: “Sclera-Choroid-RPE Transport of Eight β-Blockers in Human, Bovine, Porcine, Rabbit, and Rat Models” by Rajendra S. Kadam, Narayan P. S. Cheruvu, Henry F. Edelhauser, and Uday B. Kompella (Invest Ophthalmol Vis Sci. 2011;52:5387–5399) doi:10.1167/iovs.10-6233
A scientific misconduct investigation by University of Colorado Denver (Anschutz Medical Campus) concluded that this paper contains falsified and/or fabricated data. Specifically, Figures 1 and 3: Some LC-MS peak areas in the β-blocker transport data reported in these figures were falsified to create smooth monotonic transport curves with smaller error bars.
Tables 2, 3; Figures 2, 4, 5, 7, 8, and 10: All use the primary transport data from curves in Figures 1 and 3, hence the analyses reported will all be contaminated by falsified data from Figure 1 and/or Figure 3.
The university recommended the paper be retracted from publication and the Editor-in-Chief, David C. Beebe, agreed. The paper is therefore being retracted by ARVO from IOVS.