TABLE 1 ] .
Baseline Patient Characteristics
| Characteristic | Total | Fluid Responders | Fluid Nonresponders |
| No. of patients | 127 | 34 | 93 |
| Age, y | 50.2 ± 16.6 | 50.5 ± 16.7 | 49.1 ± 15.4 |
| Sex, % male | 56 | 52 | 58 |
| APACHE score | 101.4 ± 28.5 | 102.1 ± 30.0 | 99.5 ± 25.0 |
| Pao2/Fio2 ratio | 130 ± 65 | 118 ± 63 | 134 ± 64 |
| Prerandomization 24 h fluid balance, mL | 4,558 ± 3,335 | 4,914 ± 4,339 | 4,402 ± 2,810 |
| Fluid strategy | |||
| Liberal | 76 (60) | 12 (35)a | 64 (69)a |
| Conservative | 51 (40) | 22 (65)a | 29 (31)a |
Data presented as mean ± SD or No. (%). APACHE = Acute Physiology and Chronic Health Evaluation.
a
Denotes a significant difference between fluid responders and fluid nonresponders (P = .007).