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. 2015 Sep 17;6(28):24627–24635. doi: 10.18632/oncotarget.5685

Figure 1.

Figure 1

(A) Mutation frequency versus age in tumors of 6,969 individuals. The relationship between the two variables can be expressed as an exponential increase (P < 2.2*10−16, r = 0.36). (B) Frequency of somatic mutations in different age groups. Subjects over 80 had a mutation frequency more than 5 times higher than that of subjects under 20; the differences between all age groups are significant as measured by the Wilcoxon rank sum test.