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. 2015 Jun 30;6(28):25093–25108. doi: 10.18632/oncotarget.4437

Figure 4. Validation of miRNAs expression in HCC on the TCGA dataset.

Figure 4

A. Upregulated miRNAs expression. B. Downregulated miRNAs expression. C. Performances of the miRNAs in HCC tissue classification. For boxplots, expression values of miRNAs were log2-transformed and box width was proportional to the square root of sample size in each variant. HCC risk score was built using LASSO regression model by R software: 0.180E_miR-221 + 0.0262E_miR-21 - 0.007E_miR-223 - 0.185E_miR-130a. E_miR-n = Log 2 (expression of microRNA n). HCC, hepatocellular carcinoma; miRNA, microRNA; TCGA, Tumor Cancer Genome Atlas.