Skip to main content
. 2015 Jul 16;6(28):25856–25867. doi: 10.18632/oncotarget.4624

Figure 6. CCDC34 knockdown suppressed activation of MAPK and AKT signaling pathways.

Figure 6

T24 cells were infected with CCDC34-siRNA lentivirus for 72 hours and subjected to western blot with indicated antibodies. Control, cells infected with NC lentivirus; CCDC34-siRNA, cells infected with CCDC34-siRNA lentivirus. A. Effect of CCDC34 knockdown on phosphorylation of P-JNK (JNK/JUN pathway) and P-P38 (P38MAPK pathway). B. Effect of CCDC34 knockdown on RAF-MEK-ERK-MAPK pathway. C. Effect of CCDC34 knockdown on phosphorylation of AKT. GAPDH served as loading control.