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. 2015 Aug 7;6(29):27519–27536. doi: 10.18632/oncotarget.4823

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Copyright: © 2015 Hamdane et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A. Untransformed Ubf^fl/fl/Er-cre^+/+/p53^−/− and Ubf^wt/wt/Er-cre^+/+/p53^−/− MEFs. B. The same p53-null MEFs after transformation with SV40Tt, Ras or Ras plus Myc oncogenes. The graphics show the cell cycle distributions obtained from FACS analyses for active DNA replication (Click-iT^® EdU) and G1 and G2 DNA content (propidium iodide, PI).