Figure 4. PAUF mediated DC vaccine has a significant tumor treatment effect.

To demonstrate tumor treatment effect, mice were subcutaneously injected with A. and B. TC-1(1 × 10⁵ cells/mouse) or C. and D. EG.7 (2 × 10⁶ cells/mouse) tumor cells. Three days after tumor cells injection, mice were treated two times at one week interval with various conditional DCs (2 × 10⁶). (A and C) Scatter plot depicting tumor growth kinetics at defined time intervals. (B and D) Kaplan-Meier survival analysis of mice. **: P < 0.01.