Table 3. Associations between AOC4P expression, clinical parameters and disease-free survival/overall survival.
| Clinical parameters | Disease-free survival (months) | Overall survival (months) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| N | Mean | 95%CI | p-value# | Mean | 95%CI | p-value# | |||
| AOC4P expression | |||||||||
| <0.25 | 62 | 23.79 | 16.03 | 31.56 | 0.004* | 44.25 | 33.92 | 54.58 | 0.013* |
| ≧0.25 | 46 | 46.63 | 34.07 | 59.18 | 64.84 | 52.81 | 76.86 | ||
| Gender | |||||||||
| male | 93 | 31.68 | 24.01 | 39.36 | 0.103 | 50.72 | 42.27 | 59.17 | 0.255 |
| Female | 15 | 44.90 | 23.34 | 66.47 | 67.28 | 42.73 | 91.83 | ||
| Age | |||||||||
| <55 | 46 | 34.79 | 22.97 | 46.61 | 0.975 | 58.14 | 45.19 | 71.08 | 0.413 |
| ≧55 | 62 | 32.57 | 23.39 | 41.76 | 49.22 | 39.02 | 59.41 | ||
| Smoking | |||||||||
| Negative | 58 | 35.27 | 26.11 | 44.43 | 0.102 | 53.35 | 43.53 | 63.17 | 0.451 |
| Positive | 45 | 28.75 | 16.81 | 40.69 | 51.13 | 36.75 | 65.52 | ||
| Alcoholism | |||||||||
| Negative | 63 | 37.61 | 28.19 | 47.04 | 0.130 | 59.51 | 49.03 | 70.00 | 0.118 |
| Positive | 35 | 30.73 | 16.70 | 44.76 | 45.91 | 30.83 | 60.99 | ||
| HBV | |||||||||
| Negative | 5 | 22.49 | −16.84 | 61.81 | 0.625 | 40.09 | −16.71 | 96.89 | 0.594 |
| Positive | 102 | 34.31 | 26.84 | 41.77 | 53.89 | 45.69 | 62.09 | ||
| HCV | |||||||||
| Negative | 3 | 29.38 | −76.81 | 135.58 | 0.910 | 58.72 | −74.69 | 192.13 | 0.548 |
| Positive | 105 | 33.64 | 26.35 | 40.92 | 52.86 | 44.80 | 60.91 | ||
| Bilirubin | |||||||||
| <0.9 | 47 | 34.79 | 24.16 | 45.43 | 0.584 | 53.02 | 41.12 | 64.92 | 0.770 |
| ≧0.9 | 61 | 32.54 | 22.58 | 42.49 | 53.01 | 42.03 | 64.00 | ||
| AST | |||||||||
| <52 | 71 | 36.70 | 27.56 | 45.84 | 0.283 | 55.53 | 45.33 | 65.73 | 0.542 |
| ≧52 | 34 | 28.67 | 15.95 | 41.40 | 50.73 | 36.92 | 64.53 | ||
| ALT | |||||||||
| <111 | 86 | 35.74 | 27.26 | 44.22 | 0.450 | 53.85 | 44.51 | 63.19 | 0.819 |
| ≧111 | 15 | 26.04 | 9.37 | 42.71 | 55.55 | 35.04 | 76.06 | ||
| Alb | |||||||||
| <4 | 43 | 26.77 | 15.73 | 37.81 | 0.079 | 41.11 | 29.76 | 52.46 | 0.032* |
| ≧4 | 57 | 37.95 | 27.66 | 48.23 | 62.00 | 50.17 | 73.84 | ||
| Cr | |||||||||
| <1 | 35 | 29.15 | 16.59 | 41.70 | 0.473 | 52.00 | 37.14 | 66.87 | 0.541 |
| ≧1 | 69 | 33.95 | 24.84 | 43.06 | 52.14 | 42.06 | 62.21 | ||
| AFP | |||||||||
| <10 | 28 | 46.33 | 29.79 | 62.86 | 0.127 | 63.82 | 47.16 | 80.49 | 0.155 |
| ≧10 | 76 | 29.80 | 21.68 | 37.92 | 50.78 | 41.35 | 60.21 | ||
| Tumor size | |||||||||
| <3 | 34 | 42.41 | 28.14 | 56.68 | 0.118 | 63.24 | 48.17 | 78.31 | 0.091 |
| ≧3 | 74 | 29.43 | 21.20 | 37.66 | 48.32 | 38.96 | 57.68 | ||
| Capsule invasion | |||||||||
| Absence | 10 | 15.27 | 4.52 | 26.02 | 0.074 | 31.47 | 13.64 | 49.30 | 0.041* |
| Presence | 98 | 35.38 | 27.62 | 43.15 | 55.22 | 46.70 | 63.74 | ||
| Vessel invasion | |||||||||
| Absence | 51 | 38.97 | 29.23 | 48.72 | 0.026* | 53.18 | 43.08 | 63.27 | 0.451 |
| Presence | 57 | 28.64 | 18.10 | 39.17 | 52.88 | 40.52 | 65.24 | ||
| Stage | |||||||||
| < 2 | 70 | 35.89 | 26.41 | 45.38 | 0.546 | 57.26 | 46.88 | 67.63 | 0.389 |
| ≧2 | 38 | 29.14 | 18.22 | 40.06 | 45.21 | 32.93 | 57.49 | ||
#
Log rank test.