Table 5. Mann-Whitney U test for association between LMRs and certain variables.

Variables	Subgroup	N	Mean rank	Sum rank	U	p
Lymphovascular invasion	No	85	69.88	5939.50	1285.500	0.010
	Yes	42	52.11	2188.50
PIK3CA gene mutation	Wild type	120	62.23	7467.00	207.000	0.024
	Mutation	7	94.43	661.00

*A two-tailed p value ≤ 0.05 was considered statistically significant.