TABLE 4.
Adverse Events (All Treatment Cycles), Whether Drug-Related or Not, That Occurred in ≥10% of the Total Study Population
| No. of Patients (%), N = 50 | ||
|---|---|---|
| Adverse Event | All Grades | Grade ≥3 |
| Total | 49 (98) | 31 (62) |
| Fatigue | 29 (58) | 2 (4) |
| Anemia | 22 (44) | 8 (16) |
| Thrombocytopenia | 19 (38) | 10 (20) |
| Nausea | 19 (38) | 0 (0) |
| Decreased appetite | 18 (36) | 2 (4) |
| Constipation | 17 (34) | 1 (2) |
| Neutropenia | 16 (32) | 14 (28) |
| Back pain | 11 (22) | 2 (4) |
| Diarrhea | 11 (22) | 1 (2) |
| Cough | 10 (20) | 0 (0) |
| Dizziness | 7 (14) | 0 (0) |
| Dyspnea | 7 (14) | 0 (0) |
| Dehydration | 7 (14) | 2 (4) |
| Urinary tract infection | 7 (14) | 3 (6) |
| Anxiety | 6 (12) | 0 (0) |
| Insomnia | 6 (12) | 0 (0) |
| Vomiting | 6 (12) | 0 (0) |
| Asthenia | 5 (10) | 1 (2) |
| Pyrexia | 5 (10) | 1 (2) |
| Leukopenia | 5 (10) | 1 (2) |