Table 3. Association of the nine genes tested in the GWASs.
Bipolar: | Schizophrenia: | Major depressive disorder: | ||||
---|---|---|---|---|---|---|
PGCBD 2011 study | SWGPCCa 2014 | PGCMDD | ||||
Gene | P-value | Marker | P-value | Marker | P-value | Marker |
SFRP4 | 0.0001* | rs7807315 | NS | — | NS | — |
STK17A | NS | — | NS | — | NS | — |
RSPH9 | NS | — | 0.00009# | rs72859036 | NS | — |
DIEXF | NS | — | NS | — | NS | — |
RABGGTB | NS | — | NS | — | NS | — |
ADAM10 | NS | — | 0.00001* | rs6494035 | NS | — |
APBA2 | NS | — | NS | — | NS | — |
GABRB2 | NS | — | NS | — | NS | — |
SLC31A1 | NS | — | NS | — | NS | — |
Significant (*) and suggestive (#) P-values are given for each gene, along with the marker showing the highest association in the gene interval. In the case of RSPH9 and ADAM10 the distance of the marker from the gene is also given.
Schizophrenia Working Group of the Psychiatric Genomics Consortium.