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. 1974 Sep;29(5):578–581. doi: 10.1136/thx.29.5.578

Ventilatory drive and ventilatory response during rebreathing

Nanta Maranetra 1,2, M C F Pain 1,2
PMCID: PMC470203  PMID: 4428460

Abstract

Maranetra, N. and Pain, M. C. F. (1974). Thorax, 29, 578-581. Ventilatory drive and ventilatory response during rebreathing. The increase in inspiratory airway pressure generated against a transiently occluded airway during rebreathing is proposed as a simple index of ventilatory drive (ΔP/ΔPco2). A study of this index in 12 normal subjects and 50 patients with chronic airways obstruction demonstrated no significant difference between normals and patients in ΔP/ΔPco2 despite an overall reduction in the ventilatory response to carbon dioxide (ΔV̇e/ΔPco2) in the patients. A significant association was demonstrated between the ventilatory response to carbon dioxide, ΔP/ΔPco2 and the degree of airways obstruction. Patients with a low ΔP/ΔPco2 showed greater hypoxaemia, hypercapnia, and polycythaemia than patients with a higher ΔP/ΔPco2 for the same degree of airways obstruction.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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