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. 1975 Apr;30(2):228–233. doi: 10.1136/thx.30.2.228

Electrical alternans in cardiac tamponade.

A P Niarchos
PMCID: PMC470271  PMID: 1179321

Abstract

Of nine patients with pericardial effusion due to various causes, four developed cardiac tamponade. Electrical alternans was present in all four, being total in three and ventricular in one. The alternans corresponded very well with the clinical diagnosis of cardiac tamponade and the radiological signs of a large pericardial effusion. In two patients alternans was present even with heart rates below 100 per minute. Apart from the exact (1 : 1) type of electrical alternans, three new types are described, a 2 : 1, 3 : 1, and a varying type. It is concluded that (a) electrical alternans associated with pericardial effusion is strongly suggestive of impending or established cardiac tamponade, and (b) electrical alternans is produced when the heart is oscillating within the pericardial sac distended by fluid with a frequency equal to one-half (exact alternans), one-third (2 : 1 alternans), and one-quarter (3 : 1 alternans) of the heart rate. The aetiology and mechanism of electrical alternans are discussed.

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Selected References

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  1. BASHOUR F. A., COCHRAN P. W. THE ASSOCIATION OF ELECTRICAL ALTERNANS WITH PERICARDIAL EFFUSION. Dis Chest. 1963 Aug;44:146–153. doi: 10.1378/chest.44.2.146. [DOI] [PubMed] [Google Scholar]
  2. BERNREITER M. Unusual electrocardiographic findings in cardiac amyloidosis. J Am Med Assoc. 1956 Jun 2;161(5):441–441. doi: 10.1001/jama.1956.62970050008008c. [DOI] [PubMed] [Google Scholar]
  3. Brody D. A., Copeland G. D., Cox J. W., Jr, Keller F. W., Wennemark J. R., Warr O. S., 3rd Experimental and clinical aspects of total electrocardiographic alternation. Am J Cardiol. 1973 Feb;31(2):254–259. doi: 10.1016/0002-9149(73)91038-2. [DOI] [PubMed] [Google Scholar]
  4. COLVIN J. Electrical alternans: case report and comments on the literature. Am Heart J. 1958 Apr;55(4):513–517. doi: 10.1016/0002-8703(58)90028-0. [DOI] [PubMed] [Google Scholar]
  5. Cokkins D. V., Kelesides C., Siaterlis J., Halimos E. Augmentation of electrical alternans with lowering of the heart rate in massive pericardial effusion. A report of a case. Circulation. 1974 Jun;49(6):1254–1256. doi: 10.1161/01.cir.49.6.1254. [DOI] [PubMed] [Google Scholar]
  6. DOHERTY J. E., HARA M. The effect of citrate infusion on the electrocardiogram of the hypothermic and normothermic dog. Am Heart J. 1961 Feb;61:225–235. doi: 10.1016/0002-8703(61)90579-8. [DOI] [PubMed] [Google Scholar]
  7. Dolara A., Pozzi L. Electrical alternation of T wave without change in QRS complex. Br Heart J. 1971 Jan;33(1):161–163. doi: 10.1136/hrt.33.1.161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Eyer K. M. U wave alternans: an electrocardiographic sign of left ventricular failure. Am Heart J. 1974 Jan;87(1):41–45. doi: 10.1016/0002-8703(74)90389-5. [DOI] [PubMed] [Google Scholar]
  9. Feigenbaum H., Zaky A., Grabhorn L. L. Cardiac motion in patients with pericardial effusion. A study using reflected ultrasound. Circulation. 1966 Oct;34(4):611–619. doi: 10.1161/01.cir.34.4.611. [DOI] [PubMed] [Google Scholar]
  10. Gabor G. E., Winsberg F., Bloom H. S. Electrical and mechanical alternation in pericardial effusion. Chest. 1971 Mar;59(3):341–344. doi: 10.1378/chest.59.3.341. [DOI] [PubMed] [Google Scholar]
  11. Glover L., Baxley W. A., Dodge H. T. A quantitative evaluation of heart size measurements from chest roentgenograms. Circulation. 1973 Jun;47(6):1289–1296. doi: 10.1161/01.cir.47.6.1289. [DOI] [PubMed] [Google Scholar]
  12. KIMURA E., YOSHIDA K. A case showing electrical alternans of the T wave without change in the QRS complex. Am Heart J. 1963 Mar;65:391–395. doi: 10.1016/0002-8703(63)90014-0. [DOI] [PubMed] [Google Scholar]
  13. LAWRENCE L. T., CRONIN J. F. ELECTRICAL ALTERNANS AND PERICARDIAL TAMPONADE. Arch Intern Med. 1963 Sep;112:415–418. doi: 10.1001/archinte.1963.03860030169020. [DOI] [PubMed] [Google Scholar]
  14. LITTMANN D. ALTERNATION OF THE HEART. Circulation. 1963 Feb;27:280–291. doi: 10.1161/01.cir.27.2.280. [DOI] [PubMed] [Google Scholar]
  15. LITTMANN D., SPODICK D. H. Total electrical alternation in pericardial disease. Circulation. 1958 May;17(5):912–917. doi: 10.1161/01.cir.17.5.912. [DOI] [PubMed] [Google Scholar]
  16. McGREGOR M., BASKIND E. Electric alternans in pericardial effusion. Circulation. 1955 Jun;11(6):837–843. doi: 10.1161/01.cir.11.6.837. [DOI] [PubMed] [Google Scholar]
  17. Meurs A. A., Vos A. K., Verhey J. B., Gerbrandy J. Electrocardiogram during cardiac ruture by myocardial infarction. Br Heart J. 1970 Mar;32(2):232–235. doi: 10.1136/hrt.32.2.232. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Niarchos A. P., McKendrick C. S. Prognosis of pericarditis after acute myocardial infarction. Br Heart J. 1973 Jan;35(1):49–54. doi: 10.1136/hrt.35.1.49. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. SPODICK D. H. Electric alternation of the heart. Its relation to the kinetics and physiology of the heart during cardiac tamponade. Am J Cardiol. 1962 Aug;10:155–165. doi: 10.1016/0002-9149(62)90290-4. [DOI] [PubMed] [Google Scholar]
  20. Usher B. W., Popp R. L. Electrical alternans: mechanism in pericardial effusion. Am Heart J. 1972 Apr;83(4):459–463. doi: 10.1016/0002-8703(72)90035-x. [DOI] [PubMed] [Google Scholar]

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