Table 3.
Screening Tests for BE
| Type of study | Diagnostic accuracy |
Patient acceptability |
Costs | Primary care |
|
|---|---|---|---|---|---|
| Standard endoscopy | Population-based cross-sectional | Excellent | Poor | High | No |
| Endoscopic brush cytology | Retrospective cohort | Good | Poor | High | No |
| EndoCDx | Prospective comparative | Gooda | Poor | High | No |
| TNE | Randomized | Excellent | Moderate | High | No |
| Office-based TNE | Randomized | Good | Moderate | Moderate | Yes |
| Capsule endoscopy | Prospective comparative | Moderate | Moderate | High | Partly |
| Single-fiber endoscopy | Animal model | Unknown | Moderate | Unknown | Unknown |
| VLE | Small cross-sectional | Unknown | Moderate | Unknown | No |
| Cytosponge | Prospective comparative | Gooda | Good | Low | Yes |
| Balloon cytology | Prospective comparative | Poor | Moderate | Low | Yes |
| Microgrippers | Animal model | Unknown | Good | Unknown | No |
| Genetic susceptibility markers (blood) | Genome-wide association studies | Unknown | Excellent | Unknown | Yes |
| Stool markers (eg, methylation) | Discovery preclinical | Unknown | Excellent | Unknown | Yes |
| Blood markers (eg, proteins, miRNAs) | Discovery preclinical | Unknown | Excellent | Unknown | Yes |
a
More data are required.