Skip to main content
NCBI home page
Thorax logoLink to Thorax
. 1975 Oct;30(5):574–577. doi: 10.1136/thx.30.5.574

Pulmonary function in tropical eosinophilia before and after treatment with diethylcarbamazine.

M S Nesarajah
PMCID: PMC470330  PMID: 1198401

Abstract

Spirometric and lung volume measurements were carried out before and after treatment with diethylcarbamazine in 19 patients with tropical eosinophilia. The total lung capacity and vital capacity returned to or nearly to normal while the FEV1 and PEFR, though improved, tended to remain below normal, indicating some residual airways obstruction especially in patients whose treatment began more than one month from the onset of symptoms. The time taken for the pulmonary function to return to normal with treatment was found to be much longer than for the clinical and haematological response.

Full text

PDF
574

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Azad Khan A. K., Patra R. W., Banu S. A., Rabbee M. F. Spirometry in tropical pulmonary eosinophilia. Br J Dis Chest. 1970 Apr;64(2):107–109. doi: 10.1016/s0007-0971(70)80036-5. [DOI] [PubMed] [Google Scholar]
  2. BAKER S. J., RAJAN K. T., DEVADATTA S. Treatment of tropical eosinophilia: a controlled trial. Lancet. 1959 Aug 22;2(7095):144–147. doi: 10.1016/s0140-6736(59)90559-8. [DOI] [PubMed] [Google Scholar]
  3. CHAUDHURI R. N. Tropical eosinophilia. J Indian Med Assoc. 1956 Sep 16;27(6):195–201. [PubMed] [Google Scholar]
  4. DANARAJ T. J. The treatment of eosinophilic lung (tropical eosinophilia) with diethylcarbamazine. Q J Med. 1958 Apr;27(106):243–263. [PubMed] [Google Scholar]
  5. DONOHUGH D. L. TROPICAL EOSINOPHILIA. AN ETIOLOGIC INQUIRY. N Engl J Med. 1963 Dec 19;269:1357–1364. doi: 10.1056/NEJM196312192692507. [DOI] [PubMed] [Google Scholar]
  6. GANATRA R. D., SHETH U. K., LEWIS R. A. Diethylcarbamazine (hetrazan) in tropical eosinophilia. Indian J Med Res. 1958 Mar;46(2):205–222. [PubMed] [Google Scholar]
  7. Joshi V. V., Udwadia F. E., Gadgil R. K. Etiology of tropical eosinophilia. A study of lung biopsies and review of published reports. Am J Trop Med Hyg. 1969 Mar;18(2):231–240. [PubMed] [Google Scholar]
  8. MISRA S. S., NATH K., SHANKER A., PRAKASH S. Diethylcarbamazine (oral and parenteral therapy) in tropical pulmonary eosinophilia. J Indian Med Assoc. 1959 Mar 16;32(6):232–243. [PubMed] [Google Scholar]
  9. Narang R. K., Jain S. C. Oral diethylcarbamazine in tropical pulmonary eosinophilia. Br J Dis Chest. 1966 Apr;60(2):93–100. doi: 10.1016/s0007-0971(66)80005-0. [DOI] [PubMed] [Google Scholar]
  10. Nesarajah M. S. Pulmonary function in tropical eosinophilia. Thorax. 1972 Mar;27(2):185–187. doi: 10.1136/thx.27.2.185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. SHANKER A., BHARGAVA R. K., SHRIVASTAVA B. N. Diethylcarbamazine in tropical pulmonary eosinophilia. Br Med J. 1960 Jan 9;1(5166):100–103. doi: 10.1136/bmj.1.5166.100. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Shanker A., Gaur K. J. Tropical eosinophilia: therapeutic observations. Indian J Chest Dis. 1971 Oct;13(4):155–162. [PubMed] [Google Scholar]
  13. Udwadia F. E. Tropical eosinophilia. A correlation of clinical, histopathologic and lung function studies. Dis Chest. 1967 Oct;52(4):531–538. doi: 10.1378/chest.52.4.531. [DOI] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES