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. 1976 Aug;31(4):373–379. doi: 10.1136/thx.31.4.373

Infective endocarditis: a survey of cases in the South-East region of Scotland, 1969-72.

R H Smith, D J Radford, R A Clark, D G Julian
PMCID: PMC470444  PMID: 968793

Abstract

The incidence and characteristics of infective endocarditis were studied in a defined community over a four-year period. Seventy-eight cases were found, giving an incidence of 16 cases permillion per year. The commonest presenting features were those of infection; 53% had cardiac failure and 37% evidence of emboli when first seen. Twenty-three cases occurred on rheumatic heart valves, 13 on valvular prostheses, and 19 in previously normal hearts. Streptococcus viridans was the commonest organism, but there was a relatively high incidence of staphylococcal infection. Only four cases were preceded by dental manipulation, and no source for the infection was found in 46 patients. The mortality rate was 46%, cardiac failure and embolic phenomena accounting for 65% of deaths. It is unlikely that earlier diagnosis or cardiac surgery would have reduced the mortality appreciably.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cherubin C. E., Baden M., Kavaler F., Lerner S., Cline W. Infective endocarditis in narcotic addicts. Ann Intern Med. 1968 Dec;69(6):1091–1098. doi: 10.7326/0003-4819-69-6-1091. [DOI] [PubMed] [Google Scholar]
  2. Cherubin C. E., Neu H. C. Infective endocarditis at the Presbyterian Hospital in New York City from 1938-1967. Am J Med. 1971 Jul;51(1):83–96. doi: 10.1016/0002-9343(71)90326-3. [DOI] [PubMed] [Google Scholar]
  3. Franklin D. H., Jacques J. Pulmonary artery compression by haemorrhage from the aorta simulating pulmonary embolism. Thorax. 1974 Jan;29(1):142–144. doi: 10.1136/thx.29.1.142. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. GROSS N. J., TALL R. CLINICAL SIGNIFICANCE OF SPLINTER HAEMORRHAGES. Br Med J. 1963 Dec 14;2(5371):1496–1498. doi: 10.1136/bmj.2.5371.1496. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hayward G. W. Infective endocarditis: a changing disease. I. Br Med J. 1973 Jun 23;2(5868):706–709. doi: 10.1136/bmj.2.5868.706. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Holler J. W., Pecora J. S. Backache in bacterial endocarditis. N Y State J Med. 1970 Jul 15;70(14):1903–1905. [PubMed] [Google Scholar]
  7. King L. H., Jr, Bradley K. P., Shires D. L., Jr, Donohue J. P., Glover J. L. Bacterial endocarditis in chronic hemodialysis patients: a complication more common than previously suspected. Surgery. 1971 Apr;69(4):554–556. [PubMed] [Google Scholar]
  8. Lerner P. I., Weinstein L. Infective endocarditis in the antibiotic era. N Engl J Med. 1966 Jan 27;274(4):199–contd. doi: 10.1056/NEJM196601272740407. [DOI] [PubMed] [Google Scholar]
  9. MARMION B. P., HIGGINS F. E., BRIDGES J. B., EDWARDS A. T. A case of subacute rickettsial endocarditis; with a survey of cardiac patients for this infection. Br Med J. 1960 Oct 29;2(5208):1264–1267. doi: 10.1136/bmj.2.5208.1264. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Messner R. P., Laxdal T., Quie P. G., Williams R. C., Jr Rheumatoid factors in subacute bacterial endocarditis--bacterium, duration of disease or genetic predisposition? Ann Intern Med. 1968 Apr;68(4):746–756. doi: 10.7326/0003-4819-68-4-746. [DOI] [PubMed] [Google Scholar]
  11. PANKEY G. A. Subacute bacterial endocarditis at the University of Minnesota Hospital, 1939 through 1959. Ann Intern Med. 1961 Oct;55:550–561. doi: 10.7326/0003-4819-55-4-550. [DOI] [PubMed] [Google Scholar]
  12. RABINOVICH S., EVANS J., SMITH I. M., JANUARY L. E. A LONG-TERM VIEW OF BACTERIAL ENDOCARDITIS. 337 CASES 1924 TO 1963. Ann Intern Med. 1965 Aug;63:185–198. doi: 10.7326/0003-4819-63-2-185. [DOI] [PubMed] [Google Scholar]
  13. Turck W. P., Howitt G., Turnberg L. A., Fox H., Longson M., Matthews M. B., Das Gupta R. Chronic Q fever. Q J Med. 1976 Apr;45(178):193–217. [PubMed] [Google Scholar]

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