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British Journal of Cancer logoLink to British Journal of Cancer
. 2015 Dec 1;113(11):1640. doi: 10.1038/bjc.2015.384

Hypermethylation of the 5′ CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis

K J Manton, M L Douglas, S Netzel-Arnett, D R Fitzpatrick, D L Nicol, A W Boyd, J A Clements, T M Antalis
PMCID: PMC4705893  PMID: 26625217

Correction to: British Journal of Cancer (2005) 92, 760–769; doi:10.1038/sj.bjc.6602373

The corresponding author of the above paper, Dr TM Antalis, has received suggestions that Figure 2A in this paper may have been manipulated. Since the samples from the experiment are no longer available, Figure 2A cannot be repeated, so should be discounted.

Experimental data and analysis have been found providing support for other figures in this paper. Furthermore, the result of the paper, that the absence of Testisin mRNA in testicular tomour tissue is associated with aberrant methylation of the Testisin gene, was confirmed in a publication in 2006 by an unrelated laboratory (J Cancer Res Clin Oncol, 13: 765–770).


Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

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