Figure 5.

Cocaine enhances responding for social play behavior via dopaminergic neurotransmission (n=7). Cocaine (COC; 10 mg/kg, s.c.) increased the number of obtained rewards (a) and the breakpoint (b). This effect was prevented by pretreatment with α-flupenthixol (FLUP; 0.125 mg/kg, i.p.). Cocaine reduced the frequency of pinning (c) but did not affect the time spent on social exploration (d). The effect of cocaine on pinning was not altered by pre/treatment with α-flupenthixol. SAL, saline. Data are presented as mean+SEM. *p<0.05, **p<0.01, ***p<0.001.