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. 1977 Oct;32(5):637–642. doi: 10.1136/thx.32.5.637

Pulmonary metastases from basal-cell carcinoma of skin.

A Sakula
PMCID: PMC470805  PMID: 594948

Abstract

Although rodent ulcers are a relatively common malignant condition of the skin, pulmonary metastases arising from them are extremely rare. There have so far been only 29 authenticated reports of this condition. A further case is described of a man who, at the age of 35, developed a rodent ulcer (typical basal-cell carcinoma) on the forehead. Despite local excisions, skin grafting, and radiotherapy, the ulcer continued to recur, although there was no spread to regional lymph nodes. When he was aged 52, he developed widespread bilateral pulmonary lesions and a right pleural effusion. Thoracotomy provided a lung biopsy which showed the typical histological appearance of basal-cell carcinoma. He died aged 54, 19 years after the onset of the rodent ulcer, and necropsy confirmed that the pulmonary lesions were bloodborne metastases of basal-cell carcinoma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baxter H. A., Pirozynski W. J. Metastasizing basal cell carcinoma. Report of a case. Am J Clin Pathol. 1967 Jul;48(1):53–57. doi: 10.1093/ajcp/48.1.53. [DOI] [PubMed] [Google Scholar]
  2. COTRAN R. S. Metastasizing basal cell carcinomas. Cancer. 1961 Sep-Oct;14:1036–1040. doi: 10.1002/1097-0142(196109/10)14:5<1036::aid-cncr2820140518>3.0.co;2-k. [DOI] [PubMed] [Google Scholar]
  3. CRAWFORD H. J., JOSLIN C. A. METASTASISING BASAL-CELL CARCINOMA. J Pathol Bacteriol. 1964 Apr;87:437–440. doi: 10.1002/path.1700870229. [DOI] [PubMed] [Google Scholar]
  4. HUNT A. H. Terebrant rodent ulcer with widespread blood-borne metastases. Br J Surg. 1952 Sep;40(160):151–153. doi: 10.1002/bjs.18004016014. [DOI] [PubMed] [Google Scholar]
  5. HUNTINGTON R. W., Jr, LEVAN N. E. Basal-cell carcinoma metastatic from skin to lung. AMA Arch Derm. 1957 May;75(5):676–677. doi: 10.1001/archderm.1957.01550170044007. [DOI] [PubMed] [Google Scholar]
  6. Hall T. E., Tappan W. M., Decker J. W. Basal cell carcinoma with metastases. Report of two cases. Rocky Mt Med J. 1970 Dec;67(12):39–40. [PubMed] [Google Scholar]
  7. Hughes J. M. Metastatic basal cell carcinoma. A report of two cases and a review of literature. Clin Radiol. 1973 Jul;24(3):392–393. doi: 10.1016/s0009-9260(73)80069-8. [DOI] [PubMed] [Google Scholar]
  8. Jackson R., Adams R. H. Horrifying basal cell carcinoma: a study of 33 cases and a comparison with 435 non-horror cases and a report on four metastatic cases. J Surg Oncol. 1973 May;5(5):431–463. doi: 10.1002/jso.2930050505. [DOI] [PubMed] [Google Scholar]
  9. LATTES R., KESSLER R. W. Metastasizing basal-cell epithelioma of the skin; report of two cases. Cancer. 1951 Jul;4(4):866–878. doi: 10.1002/1097-0142(195107)4:4<866::aid-cncr2820040424>3.0.co;2-f. [DOI] [PubMed] [Google Scholar]
  10. Lakshmipathi T., Hunt K. M. Metastasizing basal-cell carcinoma. Br J Dermatol. 1967 May;79(5):267–270. doi: 10.1111/j.1365-2133.1967.tb11489.x. [DOI] [PubMed] [Google Scholar]
  11. MEADOWS R. WIDESPREAD VISCERAL METASTASES FROM A SKIN TUMOUR RESEMBLING A BASAL CELL CARCINOMA. Aust J Dermatol. 1964 Dec;7:254–256. doi: 10.1111/j.1440-0960.1964.tb01360.x. [DOI] [PubMed] [Google Scholar]
  12. Mantell B. S., Almeyda J. Metastasizing basal cell carcinoma. Br J Radiol. 1972 Aug;45(536):575–578. doi: 10.1259/0007-1285-45-536-575. [DOI] [PubMed] [Google Scholar]
  13. PICKREN J. W., KATZ A. D. Aspiration metastases from basal cell carcinoma. Cancer. 1958 Jul-Aug;11(4):783–789. doi: 10.1002/1097-0142(195807/08)11:4<783::aid-cncr2820110416>3.0.co;2-a. [DOI] [PubMed] [Google Scholar]
  14. RICHTER G. Subpleurale Lungenmetastasen bei sog. Basalzellencarcinom. Hautarzt. 1957 May;8(5):215–219. [PubMed] [Google Scholar]
  15. Sanderson K. V., Batten J. C. Adenoid cystic carcinoma of the scalp with pulmonary metastasis. Proc R Soc Med. 1975 Oct;68(10):649–650. doi: 10.1177/003591577506801021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Stell J. S., Moyer D. G., Dehne E. Basal cell epithelioma metastatic to bone. Arch Dermatol. 1966 Mar;93(3):338–340. [PubMed] [Google Scholar]
  17. Wermuth B. M., Fajardo L. F. Metastatic basal cell carcinoma. A review. Arch Pathol. 1970 Nov;90(5):458–462. [PubMed] [Google Scholar]

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