AB13. Long-term results of thulium laser resection of the prostate: a prospective study at multiple centers

Abstract

Purpose

To evaluate the long-term durability and complication rates after thulium laser resection of prostate through a prospective multiple centers study.

Materials and Methods

From November 2004 to December 2011, we prospectively studied 2216 patients with symptomatic begin prostatic hyperplasia (BPH) treated with thulium laser resection of the prostate at four medical centers. Patients were assessed on International Prostate Symptom Score (IPSS), quality of life (QoL), maximum urinary flow rate (Q_max) and postvoid residual urine (PVR). Perioperative complications were classified according to the modified Clavien classification system (CCS).

Results

Mean follow-up was 5 years (range: 1 to 8 years). Postoperatively, IPSS, QoL, Q_max and PVR showed a significant improvement from 3 month after surgery and remained significantly improved during the entire follow-up period (P<0.01). Minor complications occurred in 526 (23.7%) of the 2216 patients (Clavien 1: 21.5%; Clavien 2: 2.3%). Major complications requiring re-interventions occurred in 48 (2.2%) of the 2216 patients (Clavien 3: 2.2%). No Clavien 4 or Clavien 5 complication had occurred. Urethral stricture and bladder neck contracture occurred in 2.6% [58] and 1.6% [35] patients, respectively. Re-operation as a result of BPH recurrence was required in 1.2% [27] patients.

Conclusions

Thulium laser resection of the prostate is a safe and effective procedure with excellent durability in the treatment of symptomatic BPH.