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. 1978 Feb;33(1):97–100. doi: 10.1136/thx.33.1.97

Depression of central respiratory drive by nitrazepam.

M Rudolf, D M Geddes, J A Turner, K B Saunders
PMCID: PMC470854  PMID: 644547

Abstract

In a group of patients with chronic bronchitis, repeated night sedation with 10 mg nitrazepam produced a fall in central respiratory drive and a steady rise in arterial carbon dioxide tension. The changes produced over a five-day period were not clinically important, except in two patients who were already hypercapnic before receiving nitrazepam. The use of this drug in patients with carbon dioxide retention should be avoided.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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