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. 1978 Dec;33(6):785–790. doi: 10.1136/thx.33.6.785

Lung volumes and distensibility, and maximum respiratory pressures in thyroid disease before and after treatment.

S Freedman
PMCID: PMC470980  PMID: 746506

Abstract

Lung volumes, static pressure volume curves of the lung, and maximum respiratory pressures were measured in six patients with thyrotoxicosis and three with myxoedema before and after treatment. After treatment three of the thyrotoxic patients had increases in vital capacity of the same order as previously reported, but in contrast to previous reports, the lung volume changes were not associated with, nor due to, concomitant changes in respiratory muscle performance. Static pulmonary compliance increased in four of the six patients. The initial findings were more in keeping with the presence of pulmonary congestion. Only one of the myxoedematous patients had any significant increase in vital capacity after treatment, and in her case this was clearly attributable to increased inspiratory muscle force.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BISHOP J. M., DONALD K. W., WADE O. L. Circulatory dynamics at rest and on exercise in the hyperkinetic states. Clin Sci. 1955 May;14(2):329–360. [PubMed] [Google Scholar]
  2. BONDURANT S., HICKAM J. B., ISLEY J. K. Pulmonary and circulatory effects of acute pulmonary vascular engorgement in normal subjects. J Clin Invest. 1957 Jan;36(1 Pt 1):59–66. doi: 10.1172/JCI103410. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BROWN C. C., Jr, FRY D. L., EBERT R. V. The mechanics of pulmonary ventilation in patients with heart diseases. Am J Med. 1954 Oct;17(4):438–446. [PubMed] [Google Scholar]
  4. Black L. F., Hyatt R. E. Maximal respiratory pressures: normal values and relationship to age and sex. Am Rev Respir Dis. 1969 May;99(5):696–702. doi: 10.1164/arrd.1969.99.5.696. [DOI] [PubMed] [Google Scholar]
  5. Burack R., Edwards R. H., Green M., Jones N. L. The response to exercise before and after treatment of myxedema with thyroxine. J Pharmacol Exp Ther. 1971 Jan;176(1):212–219. [PubMed] [Google Scholar]
  6. ELDRIDGE F. L., MCILROY M. B., STONE R. W. The mechanical properties of the lungs in anoxia, anaemia and thyrotoxicosis. Clin Sci. 1956 May;15(2):353–360. [PubMed] [Google Scholar]
  7. Gibson G. J., Pride N. B., Davis J. N., Loh L. C. Pulmonary mechanics in patients with respiratory muscle weakness. Am Rev Respir Dis. 1977 Mar;115(3):389–395. doi: 10.1164/arrd.1977.115.3.389. [DOI] [PubMed] [Google Scholar]
  8. Gibson G. J., Pride N. B. Lung distensibility. The static pressure-volume curve of the lungs and its use in clinical assessment. Br J Dis Chest. 1976 Jul;70(3):143–184. doi: 10.1016/0007-0971(76)90027-9. [DOI] [PubMed] [Google Scholar]
  9. MASSUMI R. A., WINNACKER J. L. SEVERE DEPRESSION OF THE RESPIRATORY CENTER IN MYXEDEMA. Am J Med. 1964 Jun;36:876–882. doi: 10.1016/0002-9343(64)90117-2. [DOI] [PubMed] [Google Scholar]
  10. MILIC-EMILI J., MEAD J., TURNER J. M., GLAUSER E. M. IMPROVED TECHNIQUE FOR ESTIMATING PLEURAL PRESSURE FROM ESOPHAGEAL BALLOONS. J Appl Physiol. 1964 Mar;19:207–211. doi: 10.1152/jappl.1964.19.2.207. [DOI] [PubMed] [Google Scholar]
  11. Massey D. G., Becklake M. R., McKenzie J. M., Bates D. V. Circulatory and ventilatory response to exercise in thyrotoxicosis. N Engl J Med. 1967 May 18;276(20):1104–1112. doi: 10.1056/NEJM196705182762002. [DOI] [PubMed] [Google Scholar]
  12. RICHARDS D. G. B., WHITFIELD A. G. W., ARNOTT W. M., WATERHOUSE J. A. H. The lung volume in hyperkinetic states. Br Heart J. 1953 Jan;15(1):83–86. doi: 10.1136/hrt.15.1.83. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Stein M., Kimbel P., Johnson R. L. PULMONARY FUNCTION IN HYPERTHYROIDISM. J Clin Invest. 1961 Feb;40(2):348–363. doi: 10.1172/JCI104262. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Troyer A. D., Yernault J. C., Englert M. Mechanics of breathing in patients with atrial septal defect. Am Rev Respir Dis. 1977 Mar;115(3):413–421. doi: 10.1164/arrd.1977.115.3.413. [DOI] [PubMed] [Google Scholar]
  15. WASSERMANN H. P. Lung volume and respiratory muscle power in hyperthyroidism. S Afr Med J. 1962 Nov 24;36:985–989. [PubMed] [Google Scholar]
  16. WEG J. G., CALVERLY J. R., JOHNSON C. HYPOTHYROIDISM AND ALVEOLAR HYPOVENTILATION. Arch Intern Med. 1965 Mar;115:302–306. doi: 10.1001/archinte.1965.03860150046008. [DOI] [PubMed] [Google Scholar]
  17. WILSON W. R., BEDELL G. N. The pulmonary abnormalities in myxedema. J Clin Invest. 1960 Jan;39:42–55. doi: 10.1172/JCI104025. [DOI] [PMC free article] [PubMed] [Google Scholar]

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