Abstract
Thirty-one patients who were undergoing cardiopulmonary bypass for elective aortic valve replacement were studied. The effects on some aspects of lung function of intravenous methyl prednisolone, administered immediately before bypass, were assessed by measuring alveolar-arterial oxygen differences and shunt fractions. No significant differences in pulmonary function were found between the treated and control groups. The use of methyl prednisolone in this context is not justified.
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Selected References
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- BAER D. M., OSBORN J. J. The postperfusion pulmonary congestion syndrome. Am J Clin Pathol. 1960 Nov;34:442–445. doi: 10.1093/ajcp/34.5.442. [DOI] [PubMed] [Google Scholar]
- Kelman G. R., Nunn J. F. Nomograms for correction of blood Po2, Pco2, pH, and base excess for time and temperature. J Appl Physiol. 1966 Sep;21(5):1484–1490. doi: 10.1152/jappl.1966.21.5.1484. [DOI] [PubMed] [Google Scholar]
- LEE W. H., Jr, KRUMHAAR D., FONKALSRUD E. W., SCHJEIDE O. A., MALONEY J. V., Jr Denaturation of plasma proteins as a cause of morbidity and death after intracardiac operations. Surgery. 1961 Jul;50:29–39. [PubMed] [Google Scholar]
- McCredie M. Measurement of pulmonary edema in valvular heart disease. Circulation. 1967 Sep;36(3):381–386. doi: 10.1161/01.cir.36.3.381. [DOI] [PubMed] [Google Scholar]
- Wilson J. W. Treatment or prevention of pulmonary cellular damage with pharmacologic doses of corticosteroid. Surg Gynecol Obstet. 1972 Apr;134(4):675–681. [PubMed] [Google Scholar]
