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. 1980 Jan;35(1):31–36. doi: 10.1136/thx.35.1.31

Respiratory function changes after asbestos pleurisy.

P H Wright, A Hanson, L Kreel, L H Capel
PMCID: PMC471216  PMID: 7361282

Abstract

Six patients with radiographic evidence of diffuse pleural thickening after industrial asbestos exposure are described. Five had computed tomography of the thorax. All the scans showed marked circumferential pleural thickening often with calcification, and four showed no significant evidence of intrapulmonary fibrosis (asbestosis). Lung function testing showed reduction of the inspiratory capacity and the single-breath carbon monoxide transfer factor (TLCO). The transfer coefficient, calculated as the TLCO divided by the alveolar volume determined by helium dilution during the measurement of TLCO, was increased. Pseudo-static compliance curves showed markedly more negative intrapleural pressures at all lung volumes than found in normal people. These results suggest that the circumferential pleural thickening was preventing normal lung expansion despite abnormally great distending pressures. The pattern of lung function tests is sufficiently distinctive for it to be recognised in clinical practice, and suggests that the lungs are held rigidly within an abnormal pleura. The pleural thickening in our patients may have been related to the condition described as "benign asbestos pleurisy" rather than the interstitial fibrosis of asbestosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson H. A., Selikoff I. J. Pleural reactions to environmental agents. Fed Proc. 1978 Sep;37(11):2496–2500. [PubMed] [Google Scholar]
  2. Becklake M. R. Asbestos-related diseases of the lung and other organs: their epidemiology and implications for clinical practice. Am Rev Respir Dis. 1976 Jul;114(1):187–227. doi: 10.1164/arrd.1976.114.1.187. [DOI] [PubMed] [Google Scholar]
  3. Collins T. F. Pleural reaction associated with asbestos exposure. Br J Radiol. 1968 Sep;41(489):655–661. doi: 10.1259/0007-1285-41-489-655. [DOI] [PubMed] [Google Scholar]
  4. Colp C., Reichel J., Park S. S. Severe pleural restriction: the maximum static pulmonary recoil pressure as an acid in diagnosis. Chest. 1975 Jun;67(6):658–664. doi: 10.1378/chest.67.6.658. [DOI] [PubMed] [Google Scholar]
  5. EISENSTADT H. B. ASBESTOS PLEURISY. Dis Chest. 1964 Jul;46:78–81. doi: 10.1378/chest.46.1.78. [DOI] [PubMed] [Google Scholar]
  6. EISENSTADT H. B. BENIGN ASBESTOS PLEURISY. JAMA. 1965 May 3;192:419–421. doi: 10.1001/jama.1965.03080180077029. [DOI] [PubMed] [Google Scholar]
  7. Gaensler E. A., Kaplan A. I. Asbestos pleural effusion. Ann Intern Med. 1971 Feb;74(2):178–191. doi: 10.7326/0003-4819-74-2-178. [DOI] [PubMed] [Google Scholar]
  8. Gibson G. J., Pride N. B. Lung distensibility. The static pressure-volume curve of the lungs and its use in clinical assessment. Br J Dis Chest. 1976 Jul;70(3):143–184. doi: 10.1016/0007-0971(76)90027-9. [DOI] [PubMed] [Google Scholar]
  9. Kreel L. Computer tomography in the evaluation of pulmonary asbestosis. Preliminary experiences with the EMI general purpose scanner. Acta Radiol Diagn (Stockh) 1976 Jul;17(4):405–412. doi: 10.1177/028418517601700403. [DOI] [PubMed] [Google Scholar]
  10. McDonald J. C., Becklake M. R., Gibbs G. W., McDonald A. D., Rossiter C. E. The health of chrysotile asbestos mine and mill workers of Quebec. Arch Environ Health. 1974 Feb;28(2):61–68. doi: 10.1080/00039896.1974.10666438. [DOI] [PubMed] [Google Scholar]
  11. Nyiredy G. Benigne Asbestpleuritis. Prax Pneumol. 1975 Mar;29(3):166–169. [PubMed] [Google Scholar]
  12. PETTY T. L., FILLEY G. F., MITCHELL R. S. Objective functional improvement by decortication after twenty years of artificial pneumothorax for pulmonary tuberculosis. Report of a case and review of the literature. Am Rev Respir Dis. 1961 Oct;84:572–578. doi: 10.1164/arrd.1961.84.4.572. [DOI] [PubMed] [Google Scholar]
  13. Parkes W. R. Asbestosis. Lancet. 1977 Nov 19;2(8047):1081–1081. doi: 10.1016/s0140-6736(77)91919-5. [DOI] [PubMed] [Google Scholar]
  14. SAVAGE T., FLEMING H. A. Decortication of the lung in tuberculosis disease; a study of 43 cases. Thorax. 1955 Dec;10(4):293–308. doi: 10.1136/thx.10.4.293. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Sluis-Cremer G. K., Webster I. Acute pleurisy in asbestos exposed persons. Environ Res. 1972 Dec;5(4):380–392. doi: 10.1016/0013-9351(72)90040-0. [DOI] [PubMed] [Google Scholar]
  16. Turner J. M., Mead J., Wohl M. E. Elasticity of human lungs in relation to age. J Appl Physiol. 1968 Dec;25(6):664–671. doi: 10.1152/jappl.1968.25.6.664. [DOI] [PubMed] [Google Scholar]
  17. Weill H., Jones R. The chest roentgenogram as an epidemiologic tool. Report of a workshop. Arch Environ Health. 1975 Sep;30(9):435–439. doi: 10.1080/00039896.1975.10666744. [DOI] [PubMed] [Google Scholar]

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