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. 1980 Jul;35(7):519–522. doi: 10.1136/thx.35.7.519

Histological survey of the saphenous vein before its use as autologous aortocoronary bypass graft.

G Thiene, P Miazzi, M Valsecchi, M Valente, U Bortolotti, D Casarotto, V Gallucci
PMCID: PMC471325  PMID: 6968992

Abstract

A histological examination has been carried out on the saphenous veins used in 150 consecutive patients undergoing aortocoronary bypass. Morphological changes were observed frequently and consisted mainly of fibrosis of the intima and of the medial longitudinal muscular layer. Intimal fibrosis was rarely severe enough to narrow the lumen significantly. Statistical analysis disclosed that the fibrosis of the intima and the medial longitudinal muscular layer do not increase with age. The use of frozen histological sections of the saphenous vein in patients undergoing aortocoronary bypass operations could be considered in order to discard unsuitable grafts and to direct the surgeon to alternative conduits.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barboriak J. J., Batayias G. E., Pintar K., Korns M. E. Pathological changes in surgically removed aortocoronary vein grafts. Ann Thorac Surg. 1976 Jun;21(6):524–527. doi: 10.1016/s0003-4975(10)63922-7. [DOI] [PubMed] [Google Scholar]
  2. Barboriak J. J., Pintar K., Korns M. E. Atherosclerosis in aortocoronary vein grafts. Lancet. 1974 Sep 14;2(7881):621–624. doi: 10.1016/s0140-6736(74)91945-x. [DOI] [PubMed] [Google Scholar]
  3. Brody W. R., Angeli W. W., Kosek J. C. Histologic fate of the venous coronary artery bypass in dogs. Am J Pathol. 1972 Jan;66(1):111–130. [PMC free article] [PubMed] [Google Scholar]
  4. Bulkley B. H., Hutchins G. M. Accelerated "atherosclerosis". A morphologic study of 97 saphenous vein coronary artery bypass grafts. Circulation. 1977 Jan;55(1):163–169. doi: 10.1161/01.cir.55.1.163. [DOI] [PubMed] [Google Scholar]
  5. Grondin C. M., Meere C., Castonguay Y., Lepage G., Grondin P. Progressive and late obstruction of an aorto-coronary venous bypass graft. Circulation. 1971 May;43(5):698–702. doi: 10.1161/01.cir.43.5.698. [DOI] [PubMed] [Google Scholar]
  6. Kern W. H., Dermer G. B., Lindesmith G. G. The intimal proliferation in aortic-coronary saphenous vein grafts. Light and electron microscopic studies. Am Heart J. 1972 Dec;84(6):771–777. doi: 10.1016/0002-8703(72)90070-1. [DOI] [PubMed] [Google Scholar]
  7. Lawrie G. M., Lie J. T., Morris G. C., Jr, Beazley H. L. Vein graft patency and intimal proliferation after aortocoronary bypass: early and long-term angiopathologic correlations. Am J Cardiol. 1976 Dec;38(7):856–862. doi: 10.1016/0002-9149(76)90798-0. [DOI] [PubMed] [Google Scholar]
  8. Marti M. C., Bouchardy B., Cox J. N. Aorto-coronary by-pass with autogenous saphenous vein grafts: histopathological aspects. Virchows Arch A Pathol Pathol Anat. 1971;352(3):255–266. doi: 10.1007/BF00600675. [DOI] [PubMed] [Google Scholar]
  9. Spray T. L., Roberts W. C. Changes in saphenous veins used as aortocoronary bypass grafts. Am Heart J. 1977 Oct;94(4):500–516. doi: 10.1016/s0002-8703(77)80046-x. [DOI] [PubMed] [Google Scholar]
  10. Unni K. K., Kottke B. A., Titus J. L., Frye R. L., Wallace R. B., Brown A. L. Pathologic changes in aortocoronary saphenous vein grafts. Am J Cardiol. 1974 Oct 3;34(5):526–532. doi: 10.1016/0002-9149(74)90122-2. [DOI] [PubMed] [Google Scholar]
  11. Vlodaver Z., Edwards J. E. Pathologic analysis in fatal cases following saphenous vein coronary arterial bypass. Chest. 1973 Nov;64(5):555–563. doi: 10.1378/chest.64.5.555. [DOI] [PubMed] [Google Scholar]
  12. Vlodaver Z., Edwards J. E. Pathologic changes in aortic-coronary arterial saphenous vein grafts. Circulation. 1971 Oct;44(4):719–728. doi: 10.1161/01.cir.44.4.719. [DOI] [PubMed] [Google Scholar]

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