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. 1981 Mar;36(3):200–203. doi: 10.1136/thx.36.3.200

Randomised controlled trial of rehabilitation in chronic respiratory disability.

A E Cockcroft, M J Saunders, G Berry
PMCID: PMC471476  PMID: 7025334

Abstract

A randomised controlled study of the effects of exercise training in 39 patients with chronic respiratory disability was performed. Exercise training began with six weeks in a rehabilitation centre and was continued at home. The original control group attended the rehabilitation centre after the controlled part of the study. The treated group experienced subjective benefit from rehabilitation. The 12-minute walking distance increased on average from 523 m to 643 m in the treatment group and from 564 m to 607 m in the control group. The treatment effect of 77 m (SE 33 m) was significant at the 5% level. Treadmill exercise performance changed little and resting lung function was unaltered after rehabilitation. The treatment group maintained most of their improvement seven months later and the original control subjects improved after their rehabilitation. The study confirms the beneficial effects of exercise training in the chronically breathless and it suggests that the 12-minute walking distance is a useful index of changes in everyday exercise tolerance.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ambrus L., Thal S. H., Weinstein S. B., Warnecke J. Chronic obstructive pulmonary emphysema. Is exercise beneficial? Calif Med. 1967 May;106(5):354–358. [PMC free article] [PubMed] [Google Scholar]
  2. Bass H., Whitcomb J. F., Forman R. Exercise training: therapy for patients with chronic obstructive pulmonary disease. Chest. 1970 Feb;57(2):116–121. doi: 10.1378/chest.57.2.116. [DOI] [PubMed] [Google Scholar]
  3. Bassey E. J., Fentem P. H., MacDonald I. C., Scriven P. M. Self-paced walking as a method for exercise testing in elderly and young men. Clin Sci Mol Med. 1976 Dec;51(6):609–612. doi: 10.1042/cs0510609. [DOI] [PubMed] [Google Scholar]
  4. Brundin A. Physical training in severe chronic obstructive lung disease. I. Clinical course, physical working capacity and ventilation. Scand J Respir Dis. 1974;55(1):25–36. [PubMed] [Google Scholar]
  5. Christie D. Physical training in chronic obstructive lung disease. Br Med J. 1968 Apr 20;2(5598):150–151. doi: 10.1136/bmj.2.5598.150. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Cotes J. E. Response to progressive exercise: a three-index test. Br J Dis Chest. 1972 Jul;66(3):169–184. [PubMed] [Google Scholar]
  7. Degre S., Sergysels R., Messin R., Vandermoten P., Salhadin P., Denolin H., De Coster A. Hemodynamic responses to physical training in patients with chronic lung disease. Am Rev Respir Dis. 1974 Oct;110(4):395–402. doi: 10.1164/arrd.1974.110.4.395. [DOI] [PubMed] [Google Scholar]
  8. Holten K. Training effect in patients with severe ventilatory failure. Scand J Respir Dis. 1972;53(2):65–76. [PubMed] [Google Scholar]
  9. McDermott M., McDermott T. J. Digital incremental techniques applied to spirometry. Proc R Soc Med. 1977 Mar;70(3):169–171. [PMC free article] [PubMed] [Google Scholar]
  10. McGavin C. R., Gupta S. P., Lloyd E. L., McHardy G. J. Physical rehabilitation for the chronic bronchitic: results of a controlled trial of exercises in the home. Thorax. 1977 Jun;32(3):307–311. doi: 10.1136/thx.32.3.307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. McGavin C. R., Gupta S. P., McHardy G. J. Twelve-minute walking test for assessing disability in chronic bronchitis. Br Med J. 1976 Apr 3;1(6013):822–823. doi: 10.1136/bmj.1.6013.822. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Mertens D. J., Shephard R. J., Kavanagh T. Long-term exercise therapy for chronic obstructive lung disease. Respiration. 1978;35(2):96–107. doi: 10.1159/000193865. [DOI] [PubMed] [Google Scholar]
  13. PIERCE A. K., PAEZ P. N., MILLER W. F. EXERCISE TRAINING WITH THE AID OF A PORTABLE OXYGEN SUPPLY IN PATIENTS WITH EMPHYSEMA. Am Rev Respir Dis. 1965 May;91:653–659. doi: 10.1164/arrd.1965.91.5.653. [DOI] [PubMed] [Google Scholar]
  14. PIERCE A. K., TAYLOR H. F., ARCHER R. K., MILLER W. F. RESPONSES TO EXERCISE TRAINING IN PATIENTS WITH EMPHYSEMA. Arch Intern Med. 1964 Jan;113:28–36. doi: 10.1001/archinte.1964.00280070030007. [DOI] [PubMed] [Google Scholar]
  15. Paez P. N., Phillipson E. A., Masangkay M., Sproule B. J. The physiologic basis of training patients with emphysema. Am Rev Respir Dis. 1967 Jun;95(6):944–953. doi: 10.1164/arrd.1967.95.6.944. [DOI] [PubMed] [Google Scholar]
  16. Petty T. L., Nett L. M., Finigan M. M., Brink G. A., Corsello P. R. A comprehensive care program for chronic airway obstruction. Methods and preliminary evaluation of symptomatic and functional improvement. Ann Intern Med. 1969 Jun;70(6):1109–1120. doi: 10.7326/0003-4819-70-6-1109. [DOI] [PubMed] [Google Scholar]
  17. Sergysels R., De Coster A., Degre S., Denolin H. Functional evaluation of a physical rehabilitation program including breathing exercises and bicycle training in chronic obstructive lung disease. Respiration. 1979;38(2):105–111. doi: 10.1159/000194066. [DOI] [PubMed] [Google Scholar]
  18. Sinclair D. J., Ingram C. G. Controlled trial of supervised exercise training in chronic bronchitis. Br Med J. 1980 Feb 23;280(6213):519–521. doi: 10.1136/bmj.280.6213.519. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Vyas M. N., Banister E. W., Morton J. W., Grzybowski S. Response to exercise in patients with chronic airway obstruction. I. Effects of exercise training. Am Rev Respir Dis. 1971 Mar;103(3):390–400. doi: 10.1164/arrd.1971.103.3.390. [DOI] [PubMed] [Google Scholar]
  20. White S. J., Freedman L. S. Allocation of patients to treatment groups in a controlled clinical study. Br J Cancer. 1978 May;37(5):849–857. doi: 10.1038/bjc.1978.124. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Woolf C. R., Suero J. T. Alterations in lung mechanics and gas exchange following training in chronic obstructive lung disease. Dis Chest. 1969 Jan;55(1):37–44. doi: 10.1378/chest.55.1.37. [DOI] [PubMed] [Google Scholar]

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