Abstract
When left pneumonectomy was performed on 9-week-old puppies, the right lung increased in weight, volume, surface area, and number of alveoli so that at age 20 weeks these variables were the same as those of both lungs of control animals and significantly larger than those of the right lung of control animals. The adaptive response of the right lung after pneumonectomy was greater in the lower lobe than in the middle or cardiac lobes. The number of alveoli per ml and the average interalveolar wall distance, hence the surface to volume ratio, was the same in both lungs of control animals and the same in the cardiac, middle, and lower lobes of their right lungs.
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Selected References
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- Boatman E. S. A morphometric and morphological study of the lungs of rabbits after unilateral pneumonectomy. Thorax. 1977 Aug;32(4):406–417. doi: 10.1136/thx.32.4.406. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burri P. H., Dbaly J., Weibel E. R. The postnatal growth of the rat lung. I. Morphometry. Anat Rec. 1974 Apr;178(4):711–730. doi: 10.1002/ar.1091780405. [DOI] [PubMed] [Google Scholar]
- Burri P. H., Sehovic S. The adaptive response of the rat lung after bilobectomy. Am Rev Respir Dis. 1979 May;119(5):769–777. doi: 10.1164/arrd.1979.119.5.769. [DOI] [PubMed] [Google Scholar]
- CAMPBELL H., TOMKEIEFF S. I. Calculation of the internal surface of a lung. Nature. 1952 Jul 19;170(4316):116–117. [PubMed] [Google Scholar]
- Cowan M. J., Crystal R. G. Lung growth after unilateral pneumonectomy: quantitation of collagen synthesis and content. Am Rev Respir Dis. 1975 Mar;111(3):267–277. doi: 10.1164/arrd.1975.111.3.267. [DOI] [PubMed] [Google Scholar]
- Fisher J. M., Simnett J. D. Morphogenetic and proliferative changes in the regenerating lung of the rat. Anat Rec. 1973 Aug;176(4):389–395. doi: 10.1002/ar.1091760403. [DOI] [PubMed] [Google Scholar]
- Gnavi M., Pansa E., Anselmetti G. L'accrescimento e la rigenerazione del polmone (ricerche sperimentali) Minerva Chir. 1970 Nov 30;25(22):1491–1504. [PubMed] [Google Scholar]
- Holmes C., Thurlbeck W. M. Normal lung growth and response after pneumonectomy in rats at various ages. Am Rev Respir Dis. 1979 Nov;120(5):1125–1136. doi: 10.1164/arrd.1979.120.5.1125. [DOI] [PubMed] [Google Scholar]
- Inselman L. S., Mellins R. B., Brasel J. A. Effect of lung collapse on compensatory lung growth. J Appl Physiol Respir Environ Exerc Physiol. 1977 Jul;43(1):27–31. doi: 10.1152/jappl.1977.43.1.27. [DOI] [PubMed] [Google Scholar]
- Langston C., Sachdeva P., Cowan M. J., Haines J., Crystal R. G., Thurlbeck W. M. Alveolar multiplication in the contralateral lung after unilateral pneumonectomy in the rabbit. Am Rev Respir Dis. 1977 Jan;115(1):7–13. doi: 10.1164/arrd.1977.115.1.7. [DOI] [PubMed] [Google Scholar]
- Nattie E. E., Wiley C. W., Bartlett D., Jr Adaptive growth of the lung following pneumonectomy in rats. J Appl Physiol. 1974 Oct;37(4):491–495. doi: 10.1152/jappl.1974.37.4.491. [DOI] [PubMed] [Google Scholar]
- Serý Z., Keprt E., Obrucník M. Morphometric analysis of late adaptation of the residual lung following pneumonectomy in young and adult rabbits. J Thorac Cardiovasc Surg. 1969 Apr;57(4):549–557. [PubMed] [Google Scholar]
- Simnett J. D. Stimulation of cell division following unilateral collapse of the lung. Anat Rec. 1974 Dec;180(4):681–686. doi: 10.1002/ar.1091800412. [DOI] [PubMed] [Google Scholar]
- Smith B. T., Galaugher W., Thurlbeck W. M. Serum from pneumonectomized rabbits stimulates alveolar type II cell proliferation in vitro. Am Rev Respir Dis. 1980 Apr;121(4):701–707. doi: 10.1164/arrd.1980.121.4.701. [DOI] [PubMed] [Google Scholar]
- Tartterr P. I., Goss R. J. Compensatory pulmonary hypertrophy after incapacitation of one lung in the rat. J Thorac Cardiovasc Surg. 1973 Jul;66(1):147–152. [PubMed] [Google Scholar]