Skip to main content
NCBI home page
Thorax logoLink to Thorax
. 1967 Jul;22(4):375–381. doi: 10.1136/thx.22.4.375

Pulmonary nocardiosis in a 3-year-old child

M D Holdaway 1, J Kennedy 1, T Ashcroft 1, J J Kay-Butler 1,1
PMCID: PMC471651  PMID: 6035802

Abstract

Until 1960, 179 cases of infection with Nocardia asteroides had been described in the world literature. Seventeen cases in children were reported by 1963. The organism is a common saprophyte in nature with probably a world-wide distribution. Infection can be primary but is more common in patients with underlying malignancy, auto-immune disease or preceding tuberculosis. Sulphonamides, particularly sulphadiazine, are the drugs of choice in treatment; the value of antibiotics is less clearly established. The indications for surgical treatment have not yet been defined. We record a further case of primary pulmonary nocardiosis in a 3-year-old child.

Full text

PDF
375

Images in this article

376Image
on p.376
377Image
on p.377
378Image
on p.378
379Image
on p.379

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BALLENGER C. N., Jr, GOLDRING D. Nocardiosis in childhood. J Pediatr. 1957 Feb;50(2):145–169. doi: 10.1016/s0022-3476(57)80047-x. [DOI] [PubMed] [Google Scholar]
  2. BRINE J. A. HUMAN NOCARDIOSIS: A DEVELOPING CLINICAL PICTURE. Med J Aust. 1965 Mar 6;1(10):339–342. doi: 10.5694/j.1326-5377.1965.tb71699.x. [DOI] [PubMed] [Google Scholar]
  3. CARLILE W. K., HOLLEY K. E., LOGAN G. B. Fatal acute disseminated nocardiosis in a child. JAMA. 1963 May 11;184:477–480. doi: 10.1001/jama.1963.03700190095013. [DOI] [PubMed] [Google Scholar]
  4. FREESE J. W., YOUNG W. G., Jr, SEALY W. C., CONANT N. F. PULMONARY INFECTION BY NOCARDIA ASTEROIDES. FINDINGS IN ELEVEN CLINICAL CASES. J Thorac Cardiovasc Surg. 1963 Oct;46:537–547. [PubMed] [Google Scholar]
  5. HATHAWAY B. M., MASON K. N. Nocardiosis. Study of fourteen cases. Am J Med. 1962 Jun;32:903–909. doi: 10.1016/0002-9343(62)90036-0. [DOI] [PubMed] [Google Scholar]
  6. HUNTER R. A., WILLCOX D. R., WOOLF A. L. Aerobic actinomycosis with a report of a case resembling miliary tuberculosis. Guys Hosp Rep. 1954;103(2):196–206. [PubMed] [Google Scholar]
  7. LARSEN M. C., DIAMOND H. D., COLLINS H. S. Nocardia asteroides infection; a report of seven cases. AMA Arch Intern Med. 1959 May;103(5):712–725. doi: 10.1001/archinte.1959.00270050034007. [DOI] [PubMed] [Google Scholar]
  8. MURRAY J. F., FINEGOLD S. M., FROMAN S., WILL D. W. The changing spectrum of nocardiosis. A review and presentation of nine cases. Am Rev Respir Dis. 1961 Mar;83:315–330. doi: 10.1164/arrd.1961.83.3.315. [DOI] [PubMed] [Google Scholar]
  9. RUNYON E. H. Nocardia asteroides; studies of its pathogenicity and drug sensitivities. J Lab Clin Med. 1951 May;37(5):713–720. [PubMed] [Google Scholar]
  10. SEABURY J. H., DASCOMB H. E. RESULTS OF THE TREATMENT OF SYSTEMIC MYCOSES. JAMA. 1964 May 11;188:509–513. doi: 10.1001/jama.1964.03060320031007. [DOI] [PubMed] [Google Scholar]
  11. WEBSTER B. H. Bronchopulmonary nocardiosis. Am J Med Sci. 1962 Jul;244:40–43. doi: 10.1097/00000441-196207000-00005. [DOI] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES