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. 2015 Nov 9;4:e10832. doi: 10.7554/eLife.10832

Figure 8. Summary of the effects of starvation on germ cell division, stem cell maintenance, and meiotic entry.

Figure 8.

Under fed conditions, mitotic cell divisions occur throughout the progenitor zone (Crittenden et al., 2006; Maciejowski et al., 2006); GLP-1/Notch is required for stem cell maintenance (Austin and Kimble, 1987); and transient progenitors enter the meiotic cell cycle if their movement out of the progenitor zone is restricted (Cinquin et al., 2010). Under starved conditions, germ cells become quiescent; GLP-1/Notch is dispensable for stem cell maintenance; and the meiotic entry of transient progenitors is slowed or blocked.

DOI: http://dx.doi.org/10.7554/eLife.10832.025