Abstract
During the last five years 140 biopsies of the lung or pleura have been performed with a high-speed air-drill. A specially designed trephine, 2·1 mm. in bore, proved effective in obtaining adequate specimens from patients with diffuse lung lesions. With this method 111 out of 119 (93%) consecutive lung biopsies were successful in producing specimens of lung tissue for histological examination and 101 (85%) of these biopsies were diagnostically significant. Conditions such as sarcoidosis, berylliosis, alveolar proteinosis, polyarteritis nodosa, asbestosis, and diffuse interstitial pulmonary fibrosis were conclusively diagnosed. Complications were not serious and the commonest, pneumothorax, which occurred in 26% of the lung biopsies, was usually asymptomatic. The procedure is rapid and painless and breath-holding is unnecessary. It is performed under local anaesthesia and can be repeated, if required, thus having many advantages over biopsy by open thoracotomy. However, full thoracic surgical cover should be available. Indications include diffuse and localized lesions of the lung or pleura where a definitive diagnosis is required for the purpose of treatment, prognosis, or a claim for industrial compensation.
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- AVASTHI P. S., CHAKRAVARTY S. N., GUPTA S. P. Needle biopsy of the lung. J Indian Med Assoc. 1962 Sep 16;39:289–291. [PubMed] [Google Scholar]
- CHURG J., STRAUSS L. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. Am J Pathol. 1951 Mar-Apr;27(2):277–301. [PMC free article] [PubMed] [Google Scholar]
- Hausser R. Uber die diagnostische gezielete Gewebspunktion bei unklaren Lungen-, Pleura- und Mediastinalprozessen. Dtsch Med Wochenschr. 1965 Oct 8;90(41):1809–1819. doi: 10.1055/s-0028-1113425. [DOI] [PubMed] [Google Scholar]
- LAUBY V. W., BURNETT W. E., ROSEMOND G. P., TYSON R. R. VALUE AND RISK OF BIOPSY OF PULMONARY LESIONS BY NEEDLE ASPIRATION. TWENTY-ONE YEARS' EXPERIENCE. J Thorac Cardiovasc Surg. 1965 Jan;49:159–172. [PubMed] [Google Scholar]
- Martin H. E., Ellis E. B. BIOPSY BY NEEDLE PUNCTURE AND ASPIRATION. Ann Surg. 1930 Aug;92(2):169–181. doi: 10.1097/00000658-193008000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SABOUR M. S., OSMAN L. M., LEGOLVAN P. C., ISHAK K. G. Needle biopsy of the lung. Lancet. 1960 Jul 23;2(7143):182–184. doi: 10.1016/s0140-6736(60)91327-1. [DOI] [PubMed] [Google Scholar]
- SARIN L. R., BHATNAGAR L. Needle biopsy of the lung: case reports. Indian J Med Sci. 1959 Nov;13:901–904. [PubMed] [Google Scholar]
- SMITH W. G. NEEDLE BIOPSY OF THE LUNG. WITH SPECIAL REFERENCE TO DIFFUSE LUNG DISEASE AND THE USE OF A NEW NEEDLE. Thorax. 1964 Jan;19:68–78. doi: 10.1136/thx.19.1.68. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Steel S. J., Winstanley D. P. Trephine biopsy for diffuse lung lesions. Br Med J. 1967 Jul 1;3(5556):30–32. doi: 10.1136/bmj.3.5556.30. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Walton M., Skeoch T. Diagnosis of asbestosis by needle lung biopsy. Thorax. 1968 Sep;23(5):556–562. doi: 10.1136/thx.23.5.556. [DOI] [PMC free article] [PubMed] [Google Scholar]