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. 2015 Jul 14;75(14):1620–1631. doi: 10.1002/pros.23043

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© 2015 The Authors. The Prostate, published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Inflammation driven prostate progenitor expansion is testicular‐androgen independent. A: Relative mRNA expression of OVA in intact and castrated POET‐3 mice. Values of relative mRNA expression were means ± SE for n = 3 per group. B: Scheme summarizing experimental time frame of inflammation on castrated mice. C: FACS plot of infiltrated CD45⁺ cells (left panel) and LSC population (right panel) in castrated mice, with and without induction of inflammation. D: Bar graphs of LSC in androgen depleted non‐inflamed and inflamed prostates (Student's t test was determined by n = 3 animals each group; error bar = SE).