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. 1971 Jul;26(4):376–383. doi: 10.1136/thx.26.4.376

Drug-resistant tuberculosis in Waltham Forest, 1953-68

A clinical and epidemiological study

R S Francis 1
PMCID: PMC472313  PMID: 5565783

Abstract

A study of acquired and primary drug resistance in pulmonary tuberculosis has been made in the London Borough of Waltham Forest over the 15-year period 1953-68. Aetiology, clinical and bacteriological features, treatment, and prognosis are examined and contrasted for both groups of patients. The incidence of both types of resistance is compared with the national incidence and is considered in relation to Commonwealth immigration into the borough. Reasons are suggested for the decline of the acquired and the rise in the primary type of resistance. National surveys of drug-resistant tuberculosis have served a valuable purpose in focussing epidemiological attention on the many problems raised by this potentially dangerous form of the disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ASPIN J., CROSS K. W. Survival, persistence of infectivity, and control of drug resistance in pulmonary tuberculosis between 1955 and 1960 in the Wolverhampton area. Tubercle. 1962 Jun;43:119–129. doi: 10.1016/s0041-3879(62)80030-0. [DOI] [PubMed] [Google Scholar]
  2. FOX W., WIENER A., MITCHISON D. A., SELKON J. B., SUTHERLAND I. The prevalence of drug-resistant tubercle bacilli in untreated patients with pulmonary tuberculosis; a national survey, 1955-56. Tubercle. 1957 Apr;38(2):71–84. doi: 10.1016/s0041-3879(57)80001-4. [DOI] [PubMed] [Google Scholar]
  3. JANCIK E., ZELENKA M., TOUSEK J., MAKOVA M. CHEMOTHERAPY FOR PATIENTS WITH CULTURES RESISTANT TO STREPTOMYCIN, ISONIAZID AND PAS. Tubercle. 1963 Dec;44:443–445. [PubMed] [Google Scholar]
  4. MARKS J. BACTERIOLOGICAL ASPECTS OF THE NATIONAL REGISTER OF DRUG-RESISTANT TUBERCULOSIS IN ITS FIRST TWO YEARS. Mon Bull Minist Health Public Health Lab Serv. 1965 Jan;24:2–6. [PubMed] [Google Scholar]
  5. Miller A. B., Tall R., Fox W., Lefford M. J., Mitchison D. A. Primary drug resistance in pulmonary tuberculosis in Great Britain: second national survey, 1963. Tubercle. 1966 Mar;47(1):92–108. doi: 10.1016/s0041-3879(66)80053-3. [DOI] [PubMed] [Google Scholar]
  6. PINES A. TREATMENT OF PULMONARY TUBERCULOSIS WITH CULTURES RESISTANT TO TWO OR MORE DRUGS: A SERIES OF 44 PATIENTS. Tubercle. 1965 Jun;46:131–142. doi: 10.1016/s0041-3879(65)80056-3. [DOI] [PubMed] [Google Scholar]
  7. Somner A. R., Brace A. A. Late results of treatment of chronic drug-resistant pulmonary tuberculosis. Br Med J. 1966 Mar 26;1(5490):775–778. doi: 10.1136/bmj.1.5490.775. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. THOMAS H. E. A tuberculosis drug resistance register: 1956-1961. Tubercle. 1963 Mar;44:27–33. doi: 10.1016/s0041-3879(63)80056-2. [DOI] [PubMed] [Google Scholar]
  9. ZIERSKI M. TREATMENT OF PATIENTS WITH CULTURES RESISTANT TO THE PRIMARY ANTI-TUBERCULOSIS DRUGS. Tubercle. 1964 Jun;45:96–100. doi: 10.1016/s0041-3879(64)80065-9. [DOI] [PubMed] [Google Scholar]

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