Abstract
To determine the relative accuracy and efficiency of certain methods currently being used to assess bronchial architecture, results obtained with the respective techniques were compared with `true' values derived from planimetry on the bronchi of 30 subjects. Excellent comparative figures were obtained for each bronchial constituent measured (gland, cartilage, and bronchial wall areas) with the point count method and weighing paper cut-outs. The latter seemed to be the most economical from the standpoint of time saving. Results of Reid indices, acinar counts, and determinations of percentage mucous acini (applicable only to glandular structures) correlated poorly with planimetry.
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- ANDERSON A. E., Jr, FORAKER A. G. Relative dimensions of bronchioles and parenchymal spaces in lungs from normal subjects and emphysematous patients. Am J Med. 1962 Feb;32:218–226. doi: 10.1016/0002-9343(62)90291-7. [DOI] [PubMed] [Google Scholar]
- Dunnill M. S., Massarella G. R., Anderson J. A. A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema. Thorax. 1969 Mar;24(2):176–179. doi: 10.1136/thx.24.2.176. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GLYNN A. A., MICHAELS L. Bronchial biopsy in chronic bronchitis and asthma. Tip Fak Mecm. 1960 Jun;23:142–153. doi: 10.1136/thx.15.2.142. [DOI] [PubMed] [Google Scholar]
- Hale F. C., Olsen C. R., Mickey M. R., Jr The easurement of bronchial wall components. Am Rev Respir Dis. 1968 Dec;98(6):978–987. doi: 10.1164/arrd.1968.98.6.978. [DOI] [PubMed] [Google Scholar]
- Macleod L. J., Heard B. E. Area of muscle in tracheal sections in chronic bronchitis, measured by point-counting. J Pathol. 1969 Jan;97(1):157–161. doi: 10.1002/path.1710970124. [DOI] [PubMed] [Google Scholar]
- REID L. Measurement of the bronchial mucous gland layer: a diagnostic yardstick in chronic bronchitis. Thorax. 1960 Jun;15:132–141. doi: 10.1136/thx.15.2.132. [DOI] [PMC free article] [PubMed] [Google Scholar]
- RESTREPO G., HEARD B. E. The size of the bronchial glands in chronic bronchitis. J Pathol Bacteriol. 1963 Apr;85:305–310. doi: 10.1002/path.1700850207. [DOI] [PubMed] [Google Scholar]