Figure E6. Examples of RGC groups.

a, functional “fingerprint” of G₁₀ RGCs, identified as local-edge-detector (W3) cells. Light-evoked Ca²⁺ responses of n=149 cells (a₁): heat maps (top) illustrating individual responses, with response averages and firing rates estimated from Ca²⁺ signals (cf. Fig. E1a–d) below. Ganglion cell layer (a₂; experiment from Fig. 1a₂) with G₁₀ somata (green) and receptive fields (RFs, dotted) indicated. Grey circles mark cells with RFs that passed a quality criterion (Methods). Example morphology of a G₁₀ cell filled after electrical single-cell recording (a₃, cf. b). For a complete summary of the group’s properties, see SI Data 2₁₀. b, electrical single-cell recording of a G₁₀ cell: spiking responses as raster plots and mean spike rates for “chirp”, moving bar and blue/green stimuli as well as time kernel derived from noise stimulus (b₁), polar plot of responses to moving bar (b₂) and RF map (b₃) c_1,2, G_28a,b (n=100) contrast-suppressed ON RGCs with sample morphology (c₃; G_28a,b cell dye-injected after Ca²⁺ imaging). d_1,2, electrical single-cell recording of a contrast-suppressed ON RGC with different morphology (d₃ vs. c₃). e,f, G₂ direction-selective OFF RGCs (n=162) that stratify between the ChAT bands (e₃), as fingerprint (e_1,2) and exemplary electrical single-cell recording (f_1–3). Scale bars: 50 μm; grey lines in a₃,c₃,d₃,e₃: ChAT bands.