Table 2.

Regions Showing Significant Quadratic Relation Between Relaxation Parameters and Age

Region Name	Intercept	Age	Age2	P(age)2	R2
T1 relaxometry
Right frontal white matter	811.8	−3.3619	0.0559	.045	0.21
Left frontal white matter	848.3	−4.4117	2.3849	.021	0.19
Left parietal white matter	905.5	−5.5573	0.0928	.001b	0.42
Right substantia nigra	1093.8	−10.287	0.0965	.008b	0.39
T2 relaxometry
Right frontal white mattera	67.18	−0.6168	0.0088	.013	0.32
Women	67.18	−0.6168	0.0088	.013	0.32
Men	71.52	−0.6168	0.0088
Left dentate nucleus	74.62	−0.6124	0.0060	.046	0.16

^a For right frontal white matter, the quadratic model also included a term for sex, which was statistically significant (P = 0.023), indicating a difference in intercepts between men and women. Results are displayed as separate regressions for men and women having different intercepts but the same linear and quadratic terms for age.

^b Statistically significant after correcting for multiple comparison testing using the Bonferroni correction technique.