Abstract
Exudative lesions and capsular drops have been examined in a renal biopsy series of 25 diabetics and a post-mortem series of 100 consecutive diabetics. Electron microscopy of a capsular drop and an exudative lesion is described. Exudative lesions were found in 48% of the biopsies and 47% of the necropsy material. Capsular drops were found in 60% of the biopsies and 29% of the necropsy material. No correlation with age, proteinuria, hypertension, or uraemia was noted. The incidence of both types of lesion increased with the known duration of the diabetes.
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- BARRIE H. J., ASZKANAZY C. L., SMITH G. W. More glomerular changes in diabetics. Can Med Assoc J. 1952 May;66(5):428–431. [PMC free article] [PubMed] [Google Scholar]
- BOOTH E., MONTGOMERY P. O., MUIRHEAD E. E. The glomerular lesions of diabetes mellitus, cellular hyaline and acellular hyaline lesions of intercapillary glomerulosclerosis as depicted by histochemical studies. AMA Arch Intern Med. 1956 Aug;98(2):146–161. [PubMed] [Google Scholar]
- FARQUHAR M. G., HOPPER J., Jr, MOON H. D. Diabetic glomerulosclerosis: electron and light microscopic studies. Am J Pathol. 1959 Jul-Aug;35(4):721–753. [PMC free article] [PubMed] [Google Scholar]
- GELLMAN D. D., PIRANI C. L., SOOTHILL J. F., MUEHRCKE R. C., KARK R. M. Diabetic nephropathy: a clinical and pathologic study based on renal biopsies. Medicine (Baltimore) 1959 Dec;38:321–367. [PubMed] [Google Scholar]
- HALL G. F. M. The significance of atheroma of the renal arteries in Kimmelstiel-Wilson's syndrome. J Pathol Bacteriol. 1952 Jan;64(1):103–120. doi: 10.1002/path.1700640112. [DOI] [PubMed] [Google Scholar]
- HONEY G. E., PRYSE-DAVIES J., ROBERTS D. M. A survey of nephropathy in young diabetics. Q J Med. 1962 Oct;31:473–483. [PubMed] [Google Scholar]
- KOSS L. G. Hyaline material with staining reaction of fibrinoid in renal lesions in diabetes mellitus. AMA Arch Pathol. 1952 Dec;54(6):528–547. [PubMed] [Google Scholar]
- Kimmelstiel P., Wilson C. Intercapillary Lesions in the Glomeruli of the Kidney. Am J Pathol. 1936 Jan;12(1):83–98.7. [PMC free article] [PubMed] [Google Scholar]
- LANNIGAN R., BLAINEY J. D., BREWER D. B. ELECTRON MICROSCOPY OF THE DIFFUSE GLOMERULAR LESION IN DIABETES MELLITUS WITH SPECIAL REFERENCE TO EARLY CHANGES. J Pathol Bacteriol. 1964 Jul;88:255–261. [PubMed] [Google Scholar]
- LANNIGAN R. The production of chronic renal disease in rats by a single intravenous injection of aminonucleoside of puromycin and the effect of low dosage continuous hydrocortisone. Br J Exp Pathol. 1963 Jun;44:326–333. [PMC free article] [PubMed] [Google Scholar]
- LENDRUM A. C., FRASER D. S., SLIDDERS W., HENDERSON R. Studies on the character and staining of fibrin. J Clin Pathol. 1962 Sep;15:401–413. doi: 10.1136/jcp.15.5.401. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LENDRUM A. C. The hypertensive diabetic kidney as a model of the so-called collagen diseases. Can Med Assoc J. 1963 Mar 2;88:442–452. [PMC free article] [PubMed] [Google Scholar]
- MUEHRCKE R. C., KARK R. M., PIRANI C. L. Technique of percutaneous renal biopsy in the prone position. J Urol. 1955 Sep;74(3):267–277. doi: 10.1016/S0022-5347(17)67279-3. [DOI] [PubMed] [Google Scholar]
- SABOUR M. S., MACDONALD M. K., ROBSON J. S. An electron microscopic study of the human kidney in young diabetic patients with normal renal function. Diabetes. 1962 Jul-Aug;11:291–295. [PubMed] [Google Scholar]
- TAFT H. P., FINCKH E. S., JOSKE R. A. A biopsy study of the kidney in diabetes mellitus. Australas Ann Med. 1954 Aug;3(3):189–201. doi: 10.1111/imj.1954.3.3.189. [DOI] [PubMed] [Google Scholar]







