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. 1965 Mar;18(2):244–246. doi: 10.1136/jcp.18.2.244

Histochemical demonstration of gamma glutamyl transpeptidase activity in bone marrow and blood cells

Stanislaw Szmigielski 1, Joanna Litwin 1, Barbara Zupanska 1
PMCID: PMC472876  PMID: 14276165

Abstract

The demonstration by a histochemical method of gamma glutamyl transpeptidase is described. In marrow and peripheral blood it has been found useful in differentiating between normal and leukaemic myeloblasts and between marrow (short-lived) lymphocytes and lymph node (long-lived) lymphocytes. The method may also be of value in differentiating between normal and neoplastic cells.

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Selected References

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  1. ACKERMAN G. A. HISTOCHEMICAL DIFFERENTIATION DURING NEUTROPHIL DEVELOPMENT AND MATURATION. Ann N Y Acad Sci. 1964 Feb 28;113:537–565. doi: 10.1111/j.1749-6632.1964.tb40690.x. [DOI] [PubMed] [Google Scholar]
  2. ALBERT Z., ORLOWSKI M., SZEWCZUK A. Histochemical demonstration of gamma-glutamyl transpeptidase. Nature. 1961 Aug 19;191:767–768. doi: 10.1038/191767a0. [DOI] [PubMed] [Google Scholar]
  3. FLEISCHHACKER H., STACHER A. REAKTIONEN DER BLUTLYMPHOZYTEN. Med Klin. 1964 Mar 6;59:382–385. [PubMed] [Google Scholar]
  4. FODOR P. J., MILLER A., NEIDLE A., WAELSCH H. Enzymatic synthesis of glutathione by a transfer reaction. J Biol Chem. 1953 Aug;203(2):991–1002. [PubMed] [Google Scholar]
  5. KINOSHITA J. H., BALL E. G. A transpeptidation reaction between glutathione and arginine. J Biol Chem. 1953 Feb;200(2):609–617. [PubMed] [Google Scholar]
  6. REBUCK J. W., COFFMAN H. I., BLUHM G. B., BARTH C. L. A STRUCTURAL STUDY OF RETICULUM CELL AND MONOCYTE PRODUCTION WITH QUANTITATION OF LYMPHOCYTIC MODULATION OF NONMULTIPLICATIVE TYPE TO HISTIOCYTES. Ann N Y Acad Sci. 1964 Feb 28;113:595–611. doi: 10.1111/j.1749-6632.1964.tb40693.x. [DOI] [PubMed] [Google Scholar]
  7. SCHUBERT J. C., RINNEBERG H. [Cytochemical demonstration of adenosine triphosphate-splitting enzymes at pH 7.2 in human bone marrow smears]. Blut. 1962 Jul;8:282–293. doi: 10.1007/BF01632339. [DOI] [PubMed] [Google Scholar]

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