Abstract
The present evidence indicates that serum pseudocholinesterase activity is increased to about 20% above the normal level in thyrotoxicosis and decreased by about 30% in myxoedema. Treatment restores the esterase level to the average mean activity of random normal as the patient becomes euthyroid.
There is no evidence in the present investigation that any of the pseudocholinesterase variants modify these conclusions.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BARNES J. M., DAVIES D. R. Blood cholinesterase levels in workers exposed to organo-phosphorus insecticides. Br Med J. 1951 Oct 6;2(4735):816–819. doi: 10.1136/bmj.2.4735.816. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BERRY W. T., COWIN P. J., DAVIES D. R. A relationship between body fat and plasma pseudo-cholinesterase. Br J Nutr. 1954;8(2):79–82. doi: 10.1079/bjn19540016. [DOI] [PubMed] [Google Scholar]
- CALLAWAY S., DAVIES D. R., RUTLAND J. P. Blood cholinesterase levels and range of personal variation in a healthy adult population. Br Med J. 1951 Oct 6;2(4735):812–816. doi: 10.1136/bmj.2.4735.812. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HARRIS H., HOPKINSON D. A., ROBSON E. B., WHITTAKER M. Genetical studies on a new variant of serum cholinesterase detected by electrophoresis. Ann Hum Genet. 1963 Jun;26:359–382. doi: 10.1111/j.1469-1809.1963.tb01335.x. [DOI] [PubMed] [Google Scholar]
- HARRIS H., WHITTAKER M. Differential inhibition of human serum cholinesterase with fluoride: recognition of two new phenotypes. Nature. 1961 Jul 29;191:496–498. doi: 10.1038/191496a0. [DOI] [PubMed] [Google Scholar]
- HELMECZY L., NAGY E. Untersuchungen über die Aktivität der Cholinesterase des Serums und Wirkung von intravenöser Novocain-behandlung auf Psoriatiker. Acta Med Acad Sci Hung. 1954;5(1-2):109–115. [PubMed] [Google Scholar]
- KALOW W., GENEST K. A method for the detection of atypical forms of human serum cholinesterase; determination of dibucaine numbers. Can J Biochem Physiol. 1957 Jun;35(6):339–346. doi: 10.1139/y57-041. [DOI] [PubMed] [Google Scholar]
- KALOW W., STARON N. On distribution and inheritance of atypical forms of human serum cholinesterase, as indicated by dibucaine numbers. Can J Biochem Physiol. 1957 Dec;35(12):1305–1320. [PubMed] [Google Scholar]
- SCUDAMORE H. H., VORHAUS L. J., 2nd, KARK R. M. Observations on erythrocyte and plasma cholinesterase activity in dyscrasias of the blood. Blood. 1951 Dec;6(12):1260–1273. [PubMed] [Google Scholar]
- WATERLOW J. Liver choline-esterase in malnourished infants. Lancet. 1950 May 13;1(6611):908–909. doi: 10.1016/s0140-6736(50)90738-0. [DOI] [PubMed] [Google Scholar]
- WHITTAKER M. THE PSEUDOCHOLINESTERASE VARIANTS: ESTERASE LEVELS AND INCREASED RESISTANCE TO FLUORIDE. Acta Genet Stat Med. 1964;14:281–285. doi: 10.1159/000151853. [DOI] [PubMed] [Google Scholar]
