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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1966 May;19(3):244–249. doi: 10.1136/jcp.19.3.244

Importance of cardiomyopathy and cerebral ischaemia in the diagnosis of fatal coma in pregnancy

Richard C R Connor 1,2, J Hume Adams 1,2
PMCID: PMC473247  PMID: 5937609

Abstract

A case of cardiomyopathy of pregnancy where death was due to profound cerebral ischaemia is reported. Two other similar cases are mentioned. Awareness of this syndrome may help the pathologist to establish the cause of coma and death in pregnancy when clinical studies have failed to indicate the cause. It is suggested that electrocardiography should be carried out in all cases of apparent cerebrovascular accidents that occur during pregnancy or the puerperium as there may be an underlying cardiomyopathy. The nature and the possible aetiology of cardiomyopathy of pregnancy are briefly discussed.

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Selected References

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  1. BECKER F. F., TAUBE H. Myocarditis of obscure etiology associated with pregnancy. N Engl J Med. 1962 Jan 11;266:62–67. doi: 10.1056/NEJM196201112660202. [DOI] [PubMed] [Google Scholar]
  2. BRIERLEY J. B., COOPER J. E. Cerebral complications of hypotensive anaesthesia in a healthy adult. J Neurol Neurosurg Psychiatry. 1962 Feb;25:24–30. doi: 10.1136/jnnp.25.1.24. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BRIGDEN W. Uncommon myocardial diseases: the non-coronary cardiomyopathies. Lancet. 1957 Dec 21;273(7008):1243–1249. doi: 10.1016/s0140-6736(57)91537-4. [DOI] [PubMed] [Google Scholar]
  4. DOE R. P., ZINNEMAN H. H., FLINK E. B., ULSTROM R. A. Significance of the concentration of nonprotein-bound plasma cortisol in normal subjects, Cushing's syndrome, pregnancy, and during estrogen therapy. J Clin Endocrinol Metab. 1960 Nov;20:1484–1492. doi: 10.1210/jcem-20-11-1484. [DOI] [PubMed] [Google Scholar]
  5. GILCHRIST A. R. Cardiological problems in younger women; including those of pregnancy and the puerperium. Br Med J. 1963 Jan 26;1(5325):209–216. doi: 10.1136/bmj.1.5325.209. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. MEADOWS W. R. Idiopathic myocardial failure in the last trimester of pregnancy and the puerperium. Circulation. 1957 Jun;15(6):903–914. doi: 10.1161/01.cir.15.6.903. [DOI] [PubMed] [Google Scholar]
  7. PAULLEY J. W., JONES R., GREEN W. P., KANE E. P. Myocardial toxoplasmosis. Br Heart J. 1956 Jan;18(1):55–64. doi: 10.1136/hrt.18.1.55. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. POLEY R. W., FOBES C. D., HALL M. J. FUCHSINOPHILIA IN EARLY MYOCARDIAL INFARCTION. Arch Pathol. 1964 Mar;77:325–329. [PubMed] [Google Scholar]
  9. REID J. V. Postpartal cardiomyopathy. S Afr Med J. 1961 Mar 4;35:165–168. [PubMed] [Google Scholar]
  10. ROMANUL F. C., ABRAMOWICZ A. CHANGES IN BRAIN AND PIAL VESSELS IN ARTERIAL BORDER ZONES; A STUDY OF 13 CASES. Arch Neurol. 1964 Jul;11:40–65. doi: 10.1001/archneur.1964.00460190044004. [DOI] [PubMed] [Google Scholar]
  11. ROSEN S. M. Puerperal cardiomyopathy. Br Med J. 1959 Jul 4;2(5139):5–9. doi: 10.1136/bmj.2.5139.5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. SCHLESINGER M. J., REINER L. Focal myocytolysis of the heart. Am J Pathol. 1955 May-Jun;31(3):443–459. [PMC free article] [PubMed] [Google Scholar]
  13. Szekely P., Snaith L. THE HEART IN TOXAEMIA OF PREGNANCY. Br Heart J. 1947 Apr;9(2):128–137. doi: 10.1136/hrt.9.2.128. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. TWEED W. M. Acute congestive cardiac failue of unknown aetiology in pregnancy: report of a case. J Obstet Gynaecol Br Emp. 1960 Feb;67:131–135. [PubMed] [Google Scholar]

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