. Author manuscript; available in PMC: 2016 Apr 10.

Published in final edited form as: Biometrics. 2015 Jul 30;72(1):156–164. doi: 10.1111/biom.12368

Table 2.

Summary of association analysis results of the CoLaus resequencing dataset. The SKAT-O test (Lee et al., 2012) was used to test for the main rare variant effects on adiponectin levels (first row) and their effects on alcohol usage (second row). The iSKAT test was used to test for interaction effects between ADIPOQ gene and alcohol use on adiponectin levels (third-fifth rows).

Analysis	p-value
Main effects of rare variants of ADIPOQ gene on adiponectin levels	1.8e-14
Main effects of rare variants of ADIPOQ gene on alcohol usage	4.2e-02
Interaction effects of rare variants of ADIPOQ gene *alcohol on adiponectin levels	3.7e-02
Interaction effects of rare variants of ADIPOQ genealcohol on adiponectin levels, adjusting for effects of common variant chr3:188053586 and chr3:188053586alcohol	6.1e-02
Interaction effects of ADIPOQ genealcohol (chr3:188053586alcohol and rare variants*alcohol) on adiponectin levels	4.0e-02