Abstract
Aldolase was estimated in the cord blood of 81 newborn infants and phosphocreatine kinase in 87 infants. There is a wide range in the results, with some values falling in the range reported in children with muscular dystrophy or of carriers of the disease. There is no correlation of the serum enzyme levels with the infant's birth weight. High levels of phosphocreatine kinase were found in infants of mothers with pre-eclamptic toxaemia. A single estimation of cord phosphocreatine kinase and aldolase is of little help in determining whether or not an infant has muscular dystrophy.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BRUNS F. Bestimmung und Eigenschaften der Serumaldolase. Biochem Z. 1954;325(2):156–162. [PubMed] [Google Scholar]
- FORSTER G., ESCHER J. [Creatine phosphokinase in the diagnosis of myocardial infarction and myopathies]. Helv Med Acta. 1961 Sep;28:513–519. [PubMed] [Google Scholar]
- FRIEDMAN M. M., LAPAN B. Serum aldolase in the neonatal period: including a colorimetric determination of aldolase by standardization with dihydroxyacetone. J Lab Clin Med. 1958 May;51(5):745–752. [PubMed] [Google Scholar]
- GRIFFITHS P. D. SERUM LEVELS OF CREATINE PHOSPHOKINASE. J Clin Pathol. 1964 Jan;17:56–57. doi: 10.1136/jcp.17.1.56. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LEYBURN P., THOMSON W. H., WALTON J. N. An investigation of the carrier state in the Duchenne type muscular dystrophy. Ann Hum Genet. 1961 May;25:41–49. doi: 10.1111/j.1469-1809.1961.tb01495.x. [DOI] [PubMed] [Google Scholar]
- Richterich R., Rosin S., Aebi U., Rossi E. Progressive Muscular Dystrophy. V. The Identification of the Carrier State in the Duchenne Type by Serum Creatine Kinase Determination. Am J Hum Genet. 1963 Jun;15(2):133–154. [PMC free article] [PubMed] [Google Scholar]
- SCHAPIRA G., DREYFUS J. C., SCHAPIRA F. L'élévation du taux de l'aldolase sérique; test biochimique des myopathies. Sem Hop. 1953 Jun 10;29(38):1917–1920. [PubMed] [Google Scholar]
- SIBLEY J. A., FLEISHER G. A. The clinical significance of serum aldolase. Proc Staff Meet Mayo Clin. 1954 Nov 10;29(23):591–603. [PubMed] [Google Scholar]
- TANZER M. L., GILVARG C. Creatine and creatine kinase measurement. J Biol Chem. 1959 Dec;234:3201–3204. [PubMed] [Google Scholar]
- VOLK B. W., LOSNER S., ARONSON S. M., LEW H. The serum aldolase level in acute myocardial infarction. Am J Med Sci. 1956 Jul;232(1):38–passim. doi: 10.1097/00000441-195607000-00007. [DOI] [PubMed] [Google Scholar]