Abstract
A method is described for assessing thyroid status using Sephadex column chromatography of serum samples with added 125I triiodothyronine. The method is simple and inexpensive. It gave a correct diagnostic result in 97% of 258 euthyroid, 90% of 80 hyperthyroid, 78% of 59 hypothyroid, and 67% of 50 euthyroid, ill patients.
The principle of the method and its limitations are briefly discussed.
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Selected References
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- ADAMS R., SPECHT N., WOODWARF I. Labeling of erythrocytes in vitro with radioiodine-tagged I-triiodothyronine as an index of thyroid function: an improved hematocrit correction. J Clin Endocrinol Metab. 1960 Oct;20:1366–1372. doi: 10.1210/jcem-20-10-1366. [DOI] [PubMed] [Google Scholar]
- FREEDBERG A. S., HAMOLSKY M. W., STEIN M. The thyroid hormone-plasma protein complex in man. II. A new in vitro method for study of uptake of labelled hormonal components by human erythrocytes. J Clin Endocrinol Metab. 1957 Jan;17(1):33–43. doi: 10.1210/jcem-17-1-33. [DOI] [PubMed] [Google Scholar]
- MITCHELL M. L., HARDEN A. B., O'ROURKE M. E. The in vitro resin sponge uptake of triiodothyronine-I-131 from serum in thyroid disease and in pregnancy. J Clin Endocrinol Metab. 1960 Nov;20:1474–1483. doi: 10.1210/jcem-20-11-1474. [DOI] [PubMed] [Google Scholar]
- MYANT N. B., OSORIO C. Serum proteins, including thyroxine-binding proteins, in maternal and foetal rabbits. J Physiol. 1959 May 19;146(2):344–357. doi: 10.1113/jphysiol.1959.sp006196. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ROBBINS J., RALL J. E. Proteins associated with the thyroid hormones. Physiol Rev. 1960 Jul;40:415–489. doi: 10.1152/physrev.1960.40.3.415. [DOI] [PubMed] [Google Scholar]
