Table 2.
Common adverse events of Phase I trial combining neoadjuvant radiation and dendritic cell injections subdivided by grades 1–5 and total number of events during the course of the treatment.
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Total | |
|---|---|---|---|---|---|---|
| Pain | 33 | 22 | 5 | 0 | 0 | 61 |
| Rash | 16 | 0 | 0 | 0 | 0 | 16 |
| Erythema | 19 | 0 | 0 | 0 | 0 | 19 |
| Hyperglycemia | 16 | 5 | 0 | 0 | 0 | 22 |
| Limb edema | 16 | 5 | 0 | 0 | 0 | 22 |
| Hyper pigmentation | 5 | 0 | 0 | 0 | 0 | 5 |
| Injection site reactions | 11 | 5 | 0 | 0 | 0 | 16 |
| Pruritus | 5 | 0 | 0 | 0 | 0 | 5 |
| Fatigue | 66 | 33 | 0 | 0 | 0 | 99 |
| Back pain | 5 | 11 | 0 | 0 | 0 | 16 |
| Nausea | 38 | 11 | 5 | 0 | 0 | 54 |
| Bruising | 5 | 0 | 0 | 0 | 0 | 5 |
| Constipation | 44 | 11 | 0 | 0 | 0 | 55 |
| Allergic reaction/hypersensitivity | 5 | 0 | 0 | 0 | 0 | 5 |