Abstract
The results of plasma-ammonium determinations by an ion-exchange method and by a microdiffusion method were compared on the same specimens with each other and with ammonium determinations carried out on the corresponding whole-blood specimens by the microdiffusion method. The plasma-ammonium levels of whole-blood specimens were higher than those of the corresponding plasma specimens, but the difference was not constant. Recoveries of added NH4 from plasma by the microdiffusion method ranged from 65 to 144%. Recoveries of NH4 from the same specimens by the ion-exchange method ranged from 93 to 96%. Of the two, the ion-exchange method was the only one of value.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ACLAND J. D., STRONG R. PLASMA-AMMONIUM LEVELS IN CONGESTIVE CARDIAC FAILURE. Lancet. 1965 Aug 14;2(7407):345–345. [PubMed] [Google Scholar]
- BESSMAN A. N., EVANS J. M. The blood ammonia in congestive heart failure. Am Heart J. 1955 Nov;50(5):715–719. doi: 10.1016/0002-8703(55)90178-2. [DOI] [PubMed] [Google Scholar]
- BROWN R. H., DUDA G. D., KORKES S., HANDLER P. A colorimetric micromethod for determination of ammonia; the ammonia content of rat tissues and human plasma. Arch Biochem Biophys. 1957 Feb;66(2):301–309. doi: 10.1016/s0003-9861(57)80005-8. [DOI] [PubMed] [Google Scholar]
- CONN H. O. Ammonia tolerance in liver disease. J Lab Clin Med. 1960 Jun;55:855–871. [PubMed] [Google Scholar]
- DIENST S. G. An ion exchange method for plasma ammonia concentration. J Lab Clin Med. 1961 Jul;58:149–155. [PubMed] [Google Scholar]
- FENTON J. C. The estimation of plasma ammonia by ion exchange. Clin Chim Acta. 1962 Mar;7:163–175. doi: 10.1016/0009-8981(62)90004-9. [DOI] [PubMed] [Google Scholar]
- HUMOLLER F. L., BARAK A. J., HOLTHAUS J. M. DISTRIBUTION OF AMMONIA IN CELLS AND PLASMA. Clin Chem. 1964 Jul;10:589–596. [PubMed] [Google Scholar]
- SELIGSON D., HIRAHARA K. The measurement of ammonia in whole blood, erythrocytes, and plasma. J Lab Clin Med. 1957 Jun;49(6):962–974. [PubMed] [Google Scholar]