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. 2015 Dec 12;38(1):27–40. doi: 10.1002/bies.201500104

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Published 2015. This article is a U.S. Government work and is in the public domain in the USA. Bioessays published by WILEY Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Phyletic patterns of DNA adenine methylases, demethylases, and potential modified DNA‐binding domains (readers) in comparison with key components of the DNA C5 methylation apparatus. Proteins are shown along the x‐axis, whereas organisms are shown along the y‐axis according to their positions in a consensus eukaryotic phylogram. Shaded boxes (with a number) represent the presence and count of representatives in species with multiple paralogs. The blank box represents the absence. The half‐shaded box denotes the presence of the family in Trypanosoma and not Leishmania major. Species abbreviations are as in Fig. 2 legend.