Abstract
A marked increase in platelet adhesiveness was shown to occur within four hours of operation. Postoperative red cells produced greater adhesiveness in platelets from a common pool than did preoperative red cells. A greater increase in platelet adhesiveness was observed following operation with the whole blood technique than when exogenous adenosine diphosphate was added to platelet-rich plasma. Release of adenosine diphosphate from red cells so facilitated may contribute to the acute platelet-adhesiveness response to operation.
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Selected References
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- Bennett P. N. Postoperative changes in platelet adhesiveness. J Clin Pathol. 1967 Sep;20(5):708–709. doi: 10.1136/jcp.20.5.708. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bygdeman S., Eliasson R., Gullbring B. Effect of dextran infusion on the adenosine diphosphate induced adhesiveness and the spreading capacity of human blood platelets. Thromb Diath Haemorrh. 1966 May 15;15(3):451–456. [PubMed] [Google Scholar]
- Caspary E. A. Effect of red blood-cells and adenosine on platelet adhesiveness. Lancet. 1965 Dec 18;2(7425):1273–1273. doi: 10.1016/s0140-6736(65)92285-3. [DOI] [PubMed] [Google Scholar]
- GAARDER A., JONSEN J., LALAND S., HELLEM A., OWREN P. A. Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets. Nature. 1961 Nov 11;192:531–532. doi: 10.1038/192531a0. [DOI] [PubMed] [Google Scholar]
- Ham J. M., Slack W. W. Platelet adhesiveness after operation. Br J Surg. 1967 May;54(5):385–389. doi: 10.1002/bjs.1800540516. [DOI] [PubMed] [Google Scholar]
- Hampton J. R., Mitchell J. R. Abnormalities in platelet behaviour in acute illnesses. Br Med J. 1966 Apr 30;1(5495):1078–1080. doi: 10.1136/bmj.1.5495.1078. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Harrison M. J., Mitchell J. R. The influence of red blood-cells on platelet adhesiveness. Lancet. 1966 Nov 26;2(7474):1163–1164. doi: 10.1016/s0140-6736(66)90478-8. [DOI] [PubMed] [Google Scholar]
- KOEKENBERG L. J. Experimental use of macrodex as a prophylaxis against post-operative thrombo-embolism. Bull Soc Int Chir. 1962 Sep-Oct;21:501–512. [PubMed] [Google Scholar]
- MARIN H. M., STEFANINI M. Experimental production of phlebothrombosis. Surg Gynecol Obstet. 1960 Mar;110:263–268. [PubMed] [Google Scholar]
