Skip to main content
. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Stroke. 2015 Feb 5;46(3):647–652. doi: 10.1161/STROKEAHA.114.007704

Table 1.

Patient Characteristics by Neurological Deterioration Status

Any Neurological Deterioration
 First Neurological Deterioration by Category vs. No Deterioration
Yes (N=176) No (N=200) P Hyperacute (HD) (N=42) p Acute (AD) (N=81) p Subacute (SD) (N=32) P Delayed (DD) (N=15) p
Demographics
    Age (+/− StD) 68 (+/−14) 64 (+/−12) 0.003 66 0.3 67 (+/− 15) 0.06 69 (+/−12) 0.02 75 (+/− 12) 0.001
    Female Sex 73 (42%) 73 (37%) 0.3 20(48%) 0.2 30 (37%) 0.9 14 (44%) 0.4 8 (53%) 0.3
    Non-White 44 (25%) 63 (32%) 0.2 12 (29%) 0.7 21 (26%) 0.4 6 (19%) 0.2 4 (27%) 0.8
Admission Clinical Scores
    Baseline GCS 14 (11-15) 15 (14-15) <0.001 14 (13-15) 0.003 13 (11-15) <0.001 14 (10-15) 0.001 14 (11-15) 0.04
    Baseline NIHSS 16 (12-19) 12 (7-16) <0.001 15 (11-17) 0.02 16 (13-20) <0.001 17 (12-20) 0.001 15 (8-20) 0.1
Admission Vitals
    Systolic BP (mmHg) 180 (160-200) 177 (157-194) 0.2 175 (160-200) 0.8 180 (160-199) 0.2 186 (170-207) 0.05 171 (140-190) 0.6
    Diastolic BP (mmHg) 95 (80-110) 97 (84-110) 0.4 98 (80-109) 0.5 95 (81-110) 0.7 98 (85-110) 0.8 83 (70-96) 0.03
    Temperature (deg C) 36.3 (36.0-36.6) 36.5 (36.0-36.8) 0.05* 36.3 (36.2-36.6) 0.3 36.4 (36.0-36.7) 0.1 36.3 (36.0-36.8) 0.3 36.3 (35.9-36.5) 0.2
Admission Radiographic Data
    ICH Volume (ml) 23.4 (9.9-46.6) 9.4 (4.5-20.3) <0.001 23.4 (8.7-49.2) <0.001 24.4 (9.6-48.9) <0.001 19.5 (12.7-47.2) <0.001 15.0 (9.5-42.0) 0.06
    IVH Present 78 (44%) 49 (25%) <0.001 18 (43%) 0.02 31 (38%) 0.02 17 (53%) 0.001 9 (60%) 0.005
    IVH Volume (mL) 0 (0-0.2) 0 (0-0) 0.03 0 (0-0) 0.4 0 (0-0) 0.2 0 (0-3.0) 0.006 0 (0-0) 0.7
    Edema Volume (mL) 4.9 (0-21.9) 4.1 (0-11.2) 0.3 4.7 (0-14.8) 0.8 6.8 (0-30.2) 0.05* 8.7 (0-28.7) 0.2 0 (0-0.4) 0.001
    Total Blood Volume (mL) 25.7 (13.0-52.7) 11.9 (5.0-23.4) <0.001 24.9 (15.9-55.7) <0.001 28.4 (12.3-54.0) <0.001 23.4 (14.0-61.4) <0.001 22.2 (9.6-42.0) 0.04
    Lobar Location 30 (17%) 19 (10%) 0.03 6(14%) 0.4 19 (24%) 0.002 3 (9%) 1 1 (7%) 1
    Infratentorial Location 10 (6%) 12 (6%) 0.9 2(5%) 1 6 (7%) 0.8 0 (0%) 0.4 2 (13%) 0.3
Past Medical History
    Hypertension 25 (14%) 43 (22%) 0.07 8(19%) 0.8 10 (12%) 0.08 4 (13%) 0.3 1 (7%) 0.3
    Diabetes 2 (1%) 5 (3%) 0.4 0 (0%) 0.6 2 (3%) 1 0 (0%) 1.0 0 (0%) 1
    Hyperlipidemia 18 (10%) 26 (13%) 0.4 3(7%) 0.4 9 (11%) 0.8 3 (9%) 0.8 0 (0%) 0.2
    Tobacco Use 16 (9%) 23 (12%) 0.5 3 (7%) 0.6 8 (10%) 0.8 5 (16%) 0.6 0 (0%) 0.4
    Alcohol Use 15 (9%) 15 (8%) 0.7 5 (12%) 0.4 6 (7%) 1 4 (13%) 0.3 0 (0%) 0.6
Admission Laboratory Values
    Glucose (mg/dL) 124 (105-158) 114 (99-145) 0.04 124 (103-159) 0.4 129 (105-160) 0.01 121 (106-160) 0.2 112 (95-124) 0.3
    Creatinine (mg/dL) 1.0 (0.8-1.3) 1.0 (0.8-1.3) 0.7 0.9 (0.8-1.2) 0.8 1.0 (0.8-1.2) 0.7 1.0 (0.8-1.3) 0.8 0.9 (0.8-1.3) 0.8
    Sodium (mmol/L) 140 (138-142) 140 (138-142) 0.6 139 (137-141) 0.3 140 (138-142) 1 140 (138-142) 1 139 (138-142) 0.8
    INR 1.0 (0.9-1.2) 1.0 (0.9-1.1) 0.5 1.0 (0.8-1.2) 0.8 1.0 (0.9-1.2) 0.3 1.0 (0.9-1.1) 0.9 1.0 (0.9-1.2) 0.8
    aPTT (sec) 29.0 (26.0-33.3) 28.0 (26.2-31.1) 0.2 29.0 (26.3-33.0) 0.4 27.8 (25.3-32.2) 0.9 29.9 (26.4-34.0) 0.1 31.2 (27.9-36.4) 0.1
    Troponin (ug/L) 0.1 (0.05-0.25) 0.05 (0.05-0.10) 0.002 0.1 (0.05-0.25) 0.05 0.05 (0.05-0.25) 0.04 0.05 (0.05-0.25) 0.3 0.3 (0.1-0.3) 0.001
    Cholesterol (mmol/L) 5.0 (4.0-5.6) 5.1 (4.2-5.8) 0.3 4.7 (3.9-5.6) 0.5 4.8 (3.8-5.4) 0.1 5.4 (4.3-6.0) 0.3 5.2 (4.3-5.3) 0.7
    Fibrin (g/L) 4.0 (3.1-4.8) 3.8 (3.0-4.6) 0.2 3.5 (2.6-4.3) 0.3 3.8 (3.1-4.8) 0.4 4.2 (3.5-5.2) 0.02 4.7 (3.3-5.1) 0.03
    Factor 1+2 (nmol/L) 1.0 (0.6-1.5) 0.7 (0.4-1.2) 0.001 0.9 (0.5-1.4) 0.2 1.1 (0.5-1.5) 0.004 0.7 (0.5-1.3) 0.3 1.3 (0.9-2.5) 0.001

Categorical Variables are noted as N (%). Continuous variables are as noted.

Continuous variables are in the units noted followed by either +/− standard deviation or interquartile range.

*

Non-significant p-value before rounding