Abstract
The action of the venom of the gaboon viper (Bitis gabonica) on blood coagulation, platelets, and the fibrinolytic enzyme system was studied. The results confirm that the venom of Bitis gabonica has a marked anticoagulant action in vitro. The venom appears to impair clot formation by a direct proteolytic action on fibrinogen, releasing soluble breakdown products.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- CUNNINGHAM G. M., MCNICOL G. P., DOUGLAS A. S. EFFECT OF ANTICOAGULANT DRUGS ON PLATELET AGGREGATION IN THE CHANDLER'S TUBE. Lancet. 1965 Apr 3;1(7388):729–730. doi: 10.1016/s0140-6736(65)92089-1. [DOI] [PubMed] [Google Scholar]
- FLETCHER A. P., ALKJAERSIG N., SHERRY S. The maintenance of a sustained thrombolytic state in man. I. Induction and effects. J Clin Invest. 1959 Jul;38(7):1096–1110. doi: 10.1172/JCI103886. [DOI] [PMC free article] [PubMed] [Google Scholar]
- REMMERT L. F., COHEN P. P. Partial purification and properties of a proteolytic enzyme of human serum. J Biol Chem. 1949 Nov;181(1):431–448. [PubMed] [Google Scholar]
