Figure 5. Molecular pathways associated with ageing.

The network represents each pathway as individual octagonal node, while the circled nodes represent the predicted proteases that were targeted from the identified urinary peptides denoted in purple diamond nodes. The edges (links) between pathways denote an approximation of biological interaction between the pathways based on the cross-pathway feature overlap. Legends for the diamond nodes with a suffix of “-C/N” represent the peptide's cleavage site; i.e. “-C” for C-terminus and “-N” for the N-terminus.”